5 documents found, page 1 of 1
Dynamic interactions and Ca(2+)-binding modulate the holdase-type chaperone act...
Moreira, GG; Cantrelle, FX; Quezada, A; Carvalho, FS; Cristóvão, JS; Sengupta, U; Puangmalai, N; Carapeto, AP; Rodrigues, MS; Cardoso, I; Fritz, GThe microtubule-associated protein tau is implicated in the formation of oligomers and fibrillar aggregates that evade proteostasis control and spread from cell-to-cell. Tau pathology is accompanied by sustained neuroinflammation and, while the release of alarmin mediators aggravates disease at late stages, early inflammatory responses encompass protective functions. This is the case of the Ca2+-binding S100B p...
MIRRAGGE – Minimum Information Required for Reproducible AGGregation Experiments
Martins, PM; Navarro, S; Silva, A; Pinto, M; Sárkány, Z; Figueiredo, F; Pereira, PJB; Pinheiro, F; Bednarikova, Z; Burdukiewicz, M; Galzitskaya, OVReports on phase separation and amyloid formation for multiple proteins and aggregation-prone peptides are recurrently used to explore the molecular mechanisms associated with several human diseases. The information conveyed by these reports can be used directly in translational investigation, e.g., for the design of better drug screening strategies, or be compiled in databases for benchmarking novel aggregatio...
Aspiração pulmonar de conteúdo gástrico durante a extracção de balão intra-gást...
Oliveira, C; Caridade, M; Gomes, C; Gomes, CM; Domingos, R
Pulmonary aspiration of gastric contents during the extraction of intragastric ...
Oliveira, C; Gomes, CM; Caridade, M; Gomes, C; Domingos, R
Glycogen storage disease type Ia: assessment and preanesthetic management: case...
Oliveira, C; Gomes, CM; Fragoso, P; Antunes, H