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Perinatal Glyphosate-Based Herbicide Impaired Maternal Behavior by Reducing the...

Rocha, Paulo Ricardo Dell"™Armelina; Ribeiro, Miriam Oliveira; Sandini, Thaisa Meira; Camargo, Esther Lopes Ricci Adari; Bernardi, Maria Martha

AbstractGlyphosate, a non-selective herbicide, causes in mammals"™ cellular mutagenesis and toxic effects at the embryonic, fetal, and placental levels, even at low concentrations. This study investigated in rats the effects of perinatal exposure to Glyphosate-base herbicide (GLY-BH) on maternal behavior and the hypothalamic and striatal levels of dopamine and serotonin. The pup"™s physical and behavioral devel...

Date: 2019   |   Origin: Oasisbr


BEHAVIOR AS AN EARLY SIGN OF TOXICITY AND RESPIRATORY SYSTEM INJURY INDUCED BY ...

Bernardi, Maria Martha; BORGES, João Carlos Shimada; SANTOS, Douglas Amaral dos; FIGUEIREDO, Débora Alvares Leite; KIRSTEN, Thiago Berti

The aim of the present study was to determine the validity of behavior as an early sign of toxicity and respiratory injuries induced by acute exposure to cadmium in adult zebrafish (Danio rerio). The effects of three cadmium concentrations (35, 45, and 55 µg/L) on zebrafish behavior (i.e., general activity, exploratory/motor behavior, climbing to the water surface, tremors, and erratic movements) and gill histo...

Date: 2018   |   Origin: Oasisbr

A IVERMECTINA REDUZ O DIMORFISMO SEXUAL EM MODELOS COMPORTAMENTAIS DE EXPLORAÇÃ...

Bernardi, Maria Martha; Orlando, Bruna Cristina Garcia Silva; Rodrigues, Paula da Silva; Garcia, Pamela Luiz; Kirsten, Thiago Berti

As avermectinas e as milbemicinas, muitas vezes também referidas como lactonas macrocí­clicas, são os medicamentos antiparasitários mais vendidos no mundo, sendo amplamente utilizados na medicina veterinária, na agricultura e em medicina humana. O objetivo deste trabalho foi o de avaliar os efeitos sexualmente dimórficos da ivermectina (IVM) em camundongos C57BL/6 em modelos animais ligados à emocionalidade. Pa...

Date: 2018   |   Origin: Oasisbr

Periodontite materna induz prejuízos transgeracionais no desempenho reprodutivo...

Pimentel, Suzana Pires; Casati, Marcio Zaffalon; Cirano, Fabiano Ribeiro; Ribeiro, Fernanda Vieira; Casarin, Renato Corrêa Viana; Kirsten, Thiago Berti

Substantial evidence suggests a direct link between periodontitis in pregnant women and subsequent adverse pregnancy outcomes. However, no studies have evaluated the transgenerational effects of periodontitis on the reproductive performance of subsequent generations. The present study investigated whether maternal periodontal disease exerts deleterious transgenerational effects on reproductive performance in F1...

Date: 2017   |   Origin: Oasisbr


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