11 documents found, page 1 of 2

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Immune-mediated skin lesions related to biological disease-modifying antirheuma...

Martins, A.; Oliveira, D. Santos; Martins, F. R.; Nicolau, R.; Pinheiro, F. Oliveira; Rato, M.; Bernardo, A.; Pimenta, S.; Bernardes, M.; Costa, L.

Biological disease-modifying antirheumatic drugs (bDMARDs) have revolutionized the treatment of chronic inflammatory rheumatic diseases. However, the physician and the patient should be aware of possible adverse reactions. Skin is one of the most frequent organs involved in bDMARD adverse reactions and immune-mediated skin lesions (IMSL) have rarely been described before in cohort studies and their incidence is...


Adalimumab and number of previous biological disease-modifying antirheumatic dr...

Martins, A.; Oliveira, D. Santos; Martins, F. R.; Nicolau, R.; Pinheiro, F. Oliveira; Rato, M.; Bernardo, A.; Pimenta, S.; Bernardes, M.; Costa, L.

Treatment of inflammatory rheumatic diseases has dramatically changed with the introduction of biologic disease modifying anti-rheumatic drugs (bDMARDs). However, these drugs aren’t exempt from risks and skin lesions are the most frequent adverse reactions. Among the possible adverse skin reactions, immune-mediated skin lesions (IMSL) may occur. Risk factors associated with the occurrence of IMSL in rheumatic p...


Cortisol reactivity and negative affect among preterm infants at 12 months duri...

Moutinho, J.; Baptista, J.; Mesquita, A. R.; Wolke, D.; Toscano, C; Moreira, C.; Bernardo, A.; Soares, I.

The purpose of this study was to investigate correlates of preterm (PT) infant’s cortisol reactivity and the association to infant negative affect, during a mother-infant interaction procedure. Participants included 48 infants born prematurely (gestational age < 37 weeks) and their mothers, assessed when infants were 12 months old corrected for prematurity. The examined variables comprised both neonatal and env...

Date: 2023   |   Origin: Repositório ISCTE


Portuguese recommendations for the use of biological therapies in patients with...

Machado, P. M.; Cerqueira, M.; Ávila-Ribeiro, P.; Aguiar, R.; Bernardo, A.; Sepriano, A.; Águeda, A.; Cordeiro, A.; Raposo, A.; Rodrigues, A. M.


Hepatocyte growth factor signalizes peritoneal membrane failure in peritoneal d...

Bernardo, A.; Oliveira, J.; Santos, O.; Carvalho, M.; Cabrita, A.; Rodrigues, A.

BACKGROUND: Hepatocyte growth factor (HGF) counteracts peritoneal fibrosis in animal models and in-vitro studies, but no study explored effluent HGF in peritoneal dialysis (PD) patients with ultrafiltration failure (UFF). Our aim was to assess the relationship between effluent HGF with UF profile, free water transport (FWT) and small-solute transport. METHODS: We performed 4-hour, 3.86% PET with additional UF m...


Two-in-One Protocol: Simultaneous Small-Pore and Ultrasmall-Pore Peritoneal Tra...

Bernardo, A.; Bajo, A.; Santos, O.; Del Peso, G.; Carvalho, M.; Cabrita, A.; Selgas, R.; Rodrigues, A.

BACKGROUND: Reduced free water transport (FWT) through ultrasmall pores contributes to net ultrafiltration failure (UFF) and should be seen as a sign of more severe functional deterioration of the peritoneal membrane. The modified peritoneal equilibration test (PET), measuring the dip in dialysate Na concentration, estimates only FWT. Our aim was to simultaneously quantify small-solute transport, FWT, and small...



Peritoneal membrane phosphate transport status: a cornerstone in phosphate hand...

Bernardo, A.; Contesse, S.; Bajo, M.; Rodrigues, A.; Del Peso, G.; Ossorio, M.; Cabrita, A.; Selgas, R.

BACKGROUND AND OBJECTIVES: Phosphate control impacts dialysis outcomes. Our aim was to define peritoneal phosphate transport in peritoneal dialysis (PD) and to explore its association with hyperphosphatemia, phosphate clearance (PPhCl), and PD modality. DESIGN, SETTING, PARTICIPANTS, &#38; MEASUREMENTS: Two hundred sixty-four patients (61% on continuous ambulatory PD [CAPD]) were evaluated at month 12. PPhCl wa...


Avaliação da ingestão alimentar de indivíduos idosos com demência

Duarte, Maria João; Guerreiro, Catarina Sousa; Bernardo, A.; Almeida, M. C.; Mendes, Lino

A alimentação é uma das actividades básicas da vida diária que se torna um problema comum em idosos, especialmente naqueles com demência. Os principais factores que podem interferir com esta actividade básica são o ambiente onde ocorrem as refeições, a incapacidade cognitiva para iniciar e prosseguir estratégias de alimentação de uma forma eficaz, o declínio de habilidades neuromotoras e a presença de deficits ...


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