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Overview of phlorotannins’ constituents in Fucales

Catarino, Marcelo D.; Pires, Sónia M. G.; Silva, Sónia; Costa, Filipa; Braga, Susana S.; Pinto, Diana C. G. A.; Silva, Artur M. S.; Cardoso, Susana M.

Fucales are an order within the Phaeophyceae that include most of the common littoral seaweeds in temperate and subtropical coastal regions. Many species of this order have long been a part of human culture with applications as food, feedand remedies in folk medicine. Apart from their high nutritional value, these seaweeds are also a well-known reservoir of multiple bioactive compounds with great industrial int...


Plant-based beverages fortified with resveratrol complexes of β and γ cyclodext...

Silva, Andreia F. R.; Monteiro, Mariana; Fernandes, Jean Michel; Braga, Susana S.; Pinheiro, A. C.; Vicente, A. A.; Coimbra, Manuel A.

Resveratrol (RSV) is a functional ingredient with numerous bioactive properties, but precautions should be considered in the formulation of liquid food products due its poor solubility and bioavailability. In this context, cyclodextrin complexes are a viable solubilisation strategy, already applied in delivering hydrophobic compounds [1]. This study aimed at evaluating the use of and -cyclodextrin complexes wit...


Supramolecular adducts of native and permethylated β-cyclodextrins with (2,2′-d...

Braga, Susana S.; Marques, Joana; Fernandes, José A.; Paz, Filipe A. Almeida; Marques, Mª Paula M.; Santos, Teresa M.; Silva, Artur M. S.


Solid-state studies and antioxidant properties of the γ-cyclodextrin·fisetin in...

Pais, Joana M.; Barroca, Maria João; Marques, M. P. M.; Almeida Paz, Filipe A.; Braga, Susana S.

Fisetin is a natural antioxidant with a wide range of nutraceutical properties, including antidiabetic, neuroprotecting, and suppression or prevention of tumors. The present work describes the preparation of a water-soluble, solid inclusion compound of fisetin with gamma-cyclodextrin (γ-CD), a cyclic oligosaccharide approved for human consumption. A detailed physicochemical analysis of the product is carried ou...


Studies on polymorph conversion in a new cyclodextrin inclusion compound

Fernandes, José A.; Ramos, Ana I.; Ribeiro-Claro, Paulo; Almeida Paz, Filipe A.; Braga, Susana S.

A novel beta-cyclodextrin (beta CD) inclusion compound was prepared using 4-phenylpyridine-N-oxide (PPNO) as the organic guest. The inclusion compound, beta CD.PPNO, was characterised both in solution and in the solid state using numerous techniques. H-1 NMR in aqueous solution allowed the determination of a 1 : 1 stoichiometry and an association constant of 164 +/- 21 M-1. Powder and single-crystal X-ray diffr...


Carriers for metal complexes on tumour cells: the effect of cyclodextrins vs CN...

Braga, Susana S.; Marques, Joana; Heister, Elena; Diogo, Cátia V.; Oliveira, Paulo J.; Paz, Filipe A. Almeida; Santos, Teresa M.

The complex [Ru[9]aneS3(pdon)Cl]Cl (pdon = 1,10-phenanthroline-5,6-dione) was readily obtained from the stoichiometric reaction of Ru[9]aneS3(dmso)Cl2 with pdon. Recrystallisation in ethanol using salicylic acid as a co-crystallisation helper afforded single-crystals suitable for the collection of X-ray diffraction data which afforded a reasonable structural description. Two different kinds of molecular carrier...


Synthesis, Characterisation and Antiproliferative Studies of Allyl(dicarbonyl)(...

Braga, Susana S.; Mokal, Vijaya; Paz, Filipe A. Almeida; Pillinger, Martyn; Branco, Ana F.; Sardão, Vilma A.; Diogo, Cátia V.; Oliveira, Paulo J.


Synthesis, Characterisation and Antiproliferative Studies of Allyl(dicarbonyl)(...

Braga, Susana S.; Mokal, Vijaya; Almeida Paz, Filipe A.; Pillinger, Martyn; Branco, Ana F.; Sardao, Vilma A.; Diogo, Catia V.; Oliveira, Paulo J.

The complexes [(eta(5)-C5H4-CO-R)Mo(CO)(2)(eta(3)-C3H5)] [R = OH (1), Phe OMe (2)] have been examined as guests for the cyclodextrin (CD) hosts beta-CD and heptakis(2,3,6-tri-O-methyl)-beta-CD (TRIMEB), and the resultant inclusion compounds have been characterised in the solid state by elemental and thermogravimetric analyses, powder X-ray diffraction, C-13{H-1) cross-polarisation (CP) magic angle spinning (MAS...


Carriers for metal complexes on tumour cells: the effect of cyclodextrins vs CN...

Braga, Susana S.; Marques, Joana; Heister, Elena; Diogo, Catia V.; Oliveira, Paulo J.; Almeida Paz, Filipe A.; Santos, Teresa M.

The complex [Ru[9]aneS(3)(pdon)Cl]Cl (pdon = 1,10-phenanthroline-5,6-dione) was readily obtained from the stoichiometric reaction of Ru[9]aneS(3)(dmso)Cl-2 with pdon. Recrystallisation in ethanol using salicylic acid as a co-crystallisation helper afforded single-crystals suitable for the collection of X-ray diffraction data which afforded a reasonable structural description. Two different kinds of molecular ca...


Crystal Structure and Spectroscopic Studies of a Dimeric Europium( III) similar...

Coelho, Ana C.; Gomes, Ana C.; Fernandes, Jose A.; Almeida Paz, Filipe A.; Braga, Susana S.; Rino, Luis; Pereira, Luiz; Pillinger, Martyn

The homodinuclear europium(III) -diketonate complex [Eu-2(bta)(4)(pypzCH(2)COO)(2)] (1) {bta = 1-benzoyl-3,3,3-trifluoroacetonate, pypzCH(2)COO = [3-(2-pyridyl)-1-pyrazolyl]acetate} was isolated after recrystallization of the crude product obtained from the reaction of [Eu(bta)(3)(H2O)(2)] with one equivalent of the ligand phenyl[3-(2-pyridyl)-1-pyrazolyl]acetate (pypzCH(2)CO(2)C(6)H(5)). A single-crystal X-ray...


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