12 documents found, page 1 of 2
Projecting Ancient Ancestry in Modern-Day Arabians and Iranians: A Key Role of ...
Ferreira, JC; Alshamali, F; Montinaro, F; Cavadas, B; Torroni, A; Pereira, L; Raveane, A; Fernandes, VThe Arabian Peninsula is strategic for investigations centered on the early structuring of modern humans in the wake of the out-of-Africa migration. Despite its poor climatic conditions for the recovery of ancient human DNA evidence, the availability of both genomic data from neighboring ancient specimens and informative statistical tools allow modeling the ancestry of local modern populations. We applied this ...
The Comoros Show the Earliest Austronesian Gene Flow into the Swahili Corridor
Brucato, N; Fernandes, V; Mazières, S; Kusuma, P; Cox, MP; Ng'ang'aX, JW; Omar, M; Simeone-Senelle, MC; Frassati, C; Alshamali, F; Fin, B; Boland, AAt the dawn of the second millennium, the expansion of the Indian Ocean trading network aligned with the emergence of an outward-oriented community along the East African coast to create a cosmopolitan cultural and trading zone known as the Swahili Corridor. On the basis of analyses of new genome-wide genotyping data and uniparental data in 276 individuals from coastal Kenya and the Comoros islands, along with ...
Reconciling evidence from ancient and contemporary genomes: a major source for ...
Pereira, JB; Costa, MD; Vieira, D; Pala, M; Bamford, L; Harich, N; Cherni, L; Alshamali, F; Hatina, J; Rychkov, S; Stefanescu, G; King, T; Torroni, AImportant gaps remain in our understanding of the spread of farming into Europe, due partly to apparent contradictions between studies of contemporary genetic variation and ancient DNA. It seems clear that farming was introduced into central, northern, and eastern Europe from the south by pioneer colonization. It is often argued that these dispersals originated in the Near East, where the potential source genet...
60,000 years of interactions between Central and Eastern Africa documented by m...
Silva, M; Alshamali, F; Silva, P; Carrilho, C; Mandlate, F; Trovoada, MJ; Cerny, V; Pereira, L; Soares, PMitochondrial DNA (mtDNA) haplogroup L2 originated in Western Africa but is nowadays spread across the entire continent. L2 movements were previously postulated to be related to the Bantu expansion, but L2 expansions eastwards probably occurred much earlier. By reconstructing the phylogeny of L2 (44 new complete sequences) we provide insights on the complex net of within-African migrations in the last 60 thousa...
Genetic stratigraphy of key demographic events in Arabia
Fernandes, V; Triska, P; Pereira, JB; Alshamali, F; Rito, T; Machado, A; Fajkosova, Z; Cavadas, B; Cerny, V; Soares, P; Richards, MB; Pereira, LAt the crossroads between Africa and Eurasia, Arabia is necessarily a melting pot, its peoples enriched by successive gene flow over the generations. Estimating the timing and impact of these multiple migrations are important steps in reconstructing the key demographic events in the human history. However, current methods based on genome-wide information identify admixture events inefficiently, tending to estim...
The first modern human dispersals across Africa
Rito, T; Richards, MB; Fernandes, V; Alshamali, F; Cerny, V; Pereira, L; Soares, PThe emergence of more refined chronologies for climate change and archaeology in prehistoric Africa, and for the evolution of human mitochondrial DNA (mtDNA), now make it feasible to test more sophisticated models of early modern human dispersals suggested by mtDNA distributions. Here we have generated 42 novel whole-mtDNA genomes belonging to haplogroup L0, the most divergent clade in the maternal line of desc...
The expansion of mtDNA haplogroup L3 within and out of Africa
Soares, P; Alshamali, F; Pereira, JB; Fernandes, V; Silva, NM; Afonso, C; Costa, MD; Musilová, E; Macaulay, V; Richards, MB; Cerny, V; Pereira, LAlthough fossil remains show that anatomically modern humans dispersed out of Africa into the Near East ∼100 to 130 ka, genetic evidence from extant populations has suggested that non-Africans descend primarily from a single successful later migration. Within the human mitochondrial DNA (mtDNA) tree, haplogroup L3 encompasses not only many sub-Saharan Africans but also all ancient non-African lineages, and its ...
The Arabian cradle: Mitochondrial relicts of the first steps along the southern...
Fernandes, V; Alshamali, F; Alves, M; Costa, MD; Pereira, JB; Silva, NM; Cherni, L; Harich, N; Cerny, V; Soares, P; Richards, MB; Pereira, LA major unanswered question regarding the dispersal of modern humans around the world concerns the geographical site of the first human steps outside of Africa. The "southern coastal route" model predicts that the early stages of the dispersal took place when people crossed the Red Sea to southern Arabia, but genetic evidence has hitherto been tenuous. We have addressed this question by analyzing the three mino...
PopAffiliator: online calculator for individual affiliation to a major populati...
Pereira, L; Alshamali, F; Andreassen, R; Ballard, R; Chantratita, W; Cho, NS; Coudray, C; Dugoujon, JM; Espinoza, M; González-Andrade, F; Hadi, SBecause of their sensitivity and high level of discrimination, short tandem repeat (STR) maker systems are currently the method of choice in routine forensic casework and data banking, usually in multiplexes up to 15-17 loci. Constraints related to sample amount and quality, frequently encountered in forensic casework, will not allow to change this picture in the near future, notwithstanding the technological d...
Internal diversification of mitochondrial haplogroup R0a reveals post-Last Glac...
Cerny, V; Mulligan, CJ; Fernandes, V; Silva, NM; Alshamali, F; Non, A; Harich, N; Cherni, L; El Gaaied, ABA; Al-Meeri, A; Pereira, LWidespread interest in the first successful Out of Africa dispersal of modern humans ∼60-80 thousand years ago via a southern migration route has overshadowed the study of later periods of South Arabian prehistory. In this work, we show that the post-Last Glacial Maximum period of the past 20,000 years, during which climatic conditions were becoming more hospitable, has been a significant time in the formation ...