2 documents found, page 1 of 1
A Brazilian regional basic diet-induced chronic malnutrition drives liver infla...
Santos,M.J.S.; Canuto,K.M.; de Aquino,C.C.; Martins,C.S.; Brito,G.A.C.; Pessoa,T.M.R.P.; Bertolini,L.R.; de Sá Carneiro,I.; Pinto,D.V.Malnutrition is still considered endemic in many developing countries. Malnutrition-enteric infections may cause lasting deleterious effects on lipid metabolism, especially in children living in poor settings. The regional basic diet (RBD), produced to mimic the Brazilian northeastern dietary characteristics (rich in carbohydrate and low in protein) has been used in experimental malnutrition models, but few stu...
Alanyl-glutamine attenuates 5-fluorouracil-induced intestinal mucositis in apol...
Araújo,C.V.; Lazzarotto,C.R.; Aquino,C.C.; Figueiredo,I.L.; Costa,T.B.; de Oliveira Alves,L.A.; Ribeiro,R.A.; Bertolini,L.R.; Lima,A.A.M.; Brito,G.A.C.Apolipoprotein E (APOE=gene, apoE=protein) is a known factor regulating the inflammatory response that may have regenerative effects during tissue recovery from injury. We investigated whether apoE deficiency reduces the healing effect of alanyl-glutamine (Ala-Gln) treatment, a recognized gut-trophic nutrient, during tissue recovery after 5-FU-induced intestinal mucositis. APOE-knockout (APOE-/-) and wild-type ...