12 documents found, page 1 of 2

Análise de variantes no gene STK11 e sua influência na resposta à imunoterapia

Introdução: A imunoterapia é uma das ferramentas terapêuticas de sucesso usadas no tratamento do cancro de pulmão, contudo alguns doentes apresentam progressão da doença ou morte. O gene Serine/ threonine Kinase 11 (STK11) está descrito como tendo um papel na fisiologia do sistema imune (SI) e que alterações genéticas no mesmo podem influenciar negativamente a resposta dos pacientes à imunoterapia [1]. Objetivo...

Análise de variantes no gene STK11 e sua influência na resposta à imunoterapia

A imunoterapia é uma das ferramentas terapêuticas de sucesso usadas no tratamento do cancro de pulmão, contudo alguns doentes apresentam progressão da doença ou morte. O gene Serine/ threonineKinase 11 (STK11) está descrito como tendo um papel na fisiologia do sistema imune(SI) e que alterações genéticas no mesmo podem influenciar negativamente a resposta dos pacientes à imunoterapia. Estudar alterações genétic...

Anxiety and cognitive functioning in breast cancer patients treated with chemot...

Cognitive impairment in breast cancer is frequent and mostly associated to the effects of chemotherapy. Less is known about its association with anxiety symptoms, also prevalent in these patients. This study aimed to explore the possible association between anxiety symptoms and attention, processing speed, memory and executive functions in 20 breast cancer patients treated with chemotherapy. Participants with h...

Green graphene-chitosan sorbent materials for mercury water remediation

The development of new graphene-based nanocomposites able to provide synergistic effects for the adsorption of toxic heavy metals in realistic conditions (environment) is of higher demand for future applications. This work explores the preparation of a green nanocomposite based on the self-assembly of graphene oxide (GO) with chitosan (CH) for the remediation of Hg(II) in different water matrices, including ult...

The role of temperature on the impact of remediated water towards marine organisms

Marine organisms are frequently exposed to pollutants, including trace metals, derived from natural and anthropogenic activities. In order to prevent environmental pollution, di erent approaches have been applied to remove pollutants from waste water and avoid their discharge into aquatic systems. However, organisms in their natural aquatic environments are also exposed to physico-chemical changes derived from ...

Oxidative stress, metabolic and histopathological alterations in mussels expose...

The modern technology brought new engineering materials (e.g. nanostructured materials) with advantageous characteristics such as a high capacity to decontaminate water from pollutants (for example metal(loid)s). Among those innovative materials the synthesis of nanostructured materials (NSMs) based on graphene as graphene oxide (GO) functionalized with polyethyleneimine (GO-PEI) had a great success due to thei...

Graphene oxide/polyethyleneimine aerogel for high-performance mercury sorption ...

The development of effective sorbent materials to remove mercury (Hg) from real waters is a challenge. Here, we report the simple preparation of high-performance GOPEI aerogel for Hg remediation by self-assembly of high branched polyethyleneimine (PEI) with elevated molecular weight (Mw = 750 k) and graphene oxide (GO) under acidic conditions (pH < 3). Our studies revealed that the improved dimensional stabilit...

Yeast colonization of the oral cavity in a young population

Oral cavity is an environment where several kinds of fungi are frequently found. C. albicans is the most commonly isolated specie. Candida spp., besides being part of the oral mucosa in healthy individuals, constitutes an important group of opportunistic pathogenic fungi. When there is a change on oral cavity environment microorganisms excessive growth can occur, resulting in oral candidiasis. To characterize m...

Novos estilos de vida e procura habitacional - o caso dos Studio Residence no G...

Perfil alimentar do doente com excesso de peso

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