7 documents found, page 1 of 1
Rational use of antimicrobials and impact on the microbiological resistance pro...
Mesquita, Rafael Ferreira; Lima, Cicero Allan Landim de Oliveira; Lima, Luan Victor Almeida; Aquino, Bruno Pinheiro; Medeiros, Melissa SoaresThe rational use of antimicrobials has been one of the main measures to prevent the increase in antimicrobial resistance in the world. The aim of the present study was to evaluate the use of antimicrobials in a private hospital in Fortaleza/Brazil and to correlate with the increasing antimicrobial resistance. Quantitative data on bacterial infections, microbiological profile and use of antimicrobials were deter...
Development, Satisfaction and Usability of a mobile platform for monitoring the...
Ferreira, Lucas Fortaleza de Aquino; Benevides, Ana Maria Luna Neri; Rabelo, Jayanne Antonia Ferreira; Medeiros, Melissa SoaresObjective: This study aimed to develop and assess usability and satisfaction a smartphone application (App) that facilitates the screening and monitoring of emotional symptoms and factors associated with mental health in college students. Methodology: This is a cross-sectional study, with the application of questionnaires using Google Forms® among medical students at a University Center, between July 2020 and N...
Clinical outcome of patients colonized and infected by multidrug-resistant bact...
Lima, Cicero Allan Landim de Oliveira; Moreira, Ana Lívia Gomes; Mesquita, Rafael Ferreira; Lima, Luan Victor Almeida; Aquino, Bruno PinheiroThe COVID-19 pandemic, since 2019, has contributed to aggravating situations that increase the risk of colonization or infection by multidrug-resistant bacteria, such as the indiscriminate use of antimicrobials. The aim of this study was to investigate the relationship between bacterial resistance and negative clinical outcome. A cross-sectional and retrospective study was carried out, where data were collected...
Impact of antiretroviral therapy on depression and sleep disorders in HIV patients
Medeiros, Melissa Soares; Granjeiro, Liliane Nogueira; Alves, Yandra Mirelle Nogueira; Castro Junior, Jose Edvar di; Lima, Luan Victor AlmeidaDepression and sleep disorders are frequent in patients with HIV. The aim of this article is to detect sleep disorders and depression related to antiretroviral therapy in the adult population with HIV/AIDS. The following scales were applied: Patient Health Questionnaire-9 (PHQ-9), Epworth Sleepiness Scale, adapted to Brazil (ESS-Br), and the Pittsburgh Sleep Quality Index Questionnaire (PSQI). CEP: 3.319.628. I...
Polimorfismo do RRE e resistência aos antirretrovirais do vírus da imunodeficiê...
Medeiros, Melissa SoaresIntroduction: Rev Responsive Element (RRE) is a RNA molecule responsible to mRNA from HIV-1 virus nuclear transportation to cytoplasm through RRE-Rev pathway, essential to virus replication. Enfuvirtide resistance mutations are primary located in a perimeter of 10 amino acids of HR1, a corresponded region of RRE. Characterize RRE should provide a new approach for HIV therapy. Objectives: Sequence and characteri...
Microalbuminuria and kidney disease risk in HIV patients taking combined antire...
Chaves, Huylmer Lucena; Batista, Mayanna Pinho; Gomes, Adriana de Menezes; Costa, Amanda Antunes; Lima, André Tigre; Ceará, Vinícius Diniz Arcelino doObjectives: This study proposes to evaluate risk factors for kidney disease in HIV patients treated chronically and correlate with microalbuminuria measurements. Methods: Review charts and analyses of microalbuminuria in subgroup of HIV patients treated at Ceara/Brazil. Results: 149 patients, 69.1% male, mean 38.5 years old, infection mean 86.8 months. Mean Creatinine Clearance 110.2%, Creatinine 0.97, Urea 27....
Genotipagem e perfil de resistência aos antiretrovirais do virus da imunodefici...
Medeiros, Melissa SoaresGenotypic testing for HIV-1 drug resistance is useful for selecting antiretroviral drugs for patients developing treatment failure. O melhor entendimento da sua interpretação facilitará sua utilização como ferramenta médica na terapêutica do HIV. The optimal understanding of its interpretation will give an important tool for HIV treatment. Objective: To identify common combinations of resistance mutations and a...