Background: Occupational exposure as a firefighter has been recently classified as carcinogenic to humans (Group 1) by the International Agency for Research on Cancer (IARC) [1]. Polycyclic aromatic hydrocarbons (PAH) are one of the main fire-related pollutants [3], and their presence in the breathable air of firefighters was already demonstrated [4]. However, the toxicity mechanisms involved in such exposures ...