3 documents found, page 1 of 1
Involvement of nitric oxide on bothropoides insularis venom biological effects ...
De Menezes, Ramon R.P.P.B.; Mello, Clarissa P.; Lima, Dânya B.; Tessarolo, Louise D.; Sampaio, Tiago Lima; Paes, Lívia C.F.; Alves, Natacha T.Q.Made available in DSpace on 2018-12-11T17:01:56Z (GMT). No. of bitstreams: 0 Previous issue date: 2016-03-01; Viperidae venom has several local and systemic effects, such as pain, edema, inflammation, kidney failure and coagulopathy. Additionally, bothropic venom and its isolated components directly interfere on cellular metabolism, causing alterations such as cell death and proliferation. Inflammatory cells ar...
Renal tubular dysfunction in sickle cell disease
Silva Junior, Geraldo B.; Vieira, Ana Patrícia F.; Bem, Amanda X. Couto; Alves, Marília P.; Meneses, Gdayllon C.; Martins, Alice M.C.Background/Aims: Kidney abnormalities are one of the main chronic complications of sickle cell disease (SCD). The aim of this study is to investigate the occurrence of renal tubular abnormalities among patients with SCD. Methods: This is a prospective study with 26 SCD adult patients in Brazil. Urinary acidification and concentration tests were performed using calcium chloride (CaCl2), after a 12h period of wat...
Isolation, homology modeling and renal effects of a C-type natriuretic peptide ...
Alves, Renata S.; Ximenes, Rafael M.; Jorge, Antonio R.C.; Nascimento, Nilberto R.F.; Martins, René D.; Rabello, Marcelo M.; Hernandes, Marcelo Z.Submitted by Vitor Silverio Rodrigues (vitorsrodrigues@reitoria.unesp.br) on 2014-05-27T11:30:52Z No. of bitstreams: 0; Made available in DSpace on 2014-05-27T11:30:52Z (GMT). No. of bitstreams: 0 Previous issue date: 2013-11-01; Mammalian natriuretic peptides (NPs) have been extensively investigated for use as therapeutic agents in the treatment of cardiovascular diseases. Here, we describe the isolation, sequ...