6 documents found, page 1 of 1
Reliability of point-of-care circulating cathodic antigen assay for diagnosing ...
Favre, Tereza Cristina; Beck, Lilian Christina Nóbrega Holsback; Bezerra, Fernando Schemelzer Moraes; Graeff-Teixeira, Carlos; Coelho, Paulo Marcos ZechFundação Oswaldo Cruz, Instituto Oswaldo Cruz. Laboratório de Educação em Ambiente e Saúde. Rio de Janeiro, RJ, Brasil.; Fundação Oswaldo Cruz, Instituto Oswaldo Cruz. Laboratório de Educação em Ambiente e Saúde. Rio de Janeiro, RJ, Brasil.; Universidade Federal do Ceará. Departamento de Análises Clínicas e Toxicológicas. Fortaleza, CE, Brasil.; Universidade Federal do Espírito Santo. Centro de Ciências da Saúd...
Low specificity of point-of-care circulating cathodic antigen (POC[sbnd]CCA) di...
Graeff-Teixeira, Carlos; Favero, Vivian; Pascoal, Vanessa Fey; Souza, Renata Perotto de; Rigo, Francine de Vargas; Agnese, Luis Hoffmann DallThis work was funded by the Secretaria de Vigil?ncia em Sa?de / Fundo Nacional de Sa?de / Minist?rio da Sa?de (SVS/FNS/MS) - [TED/FNS: 118/2017; SIAFI: 691919/25000.479741/2017?05].; Universidade Federal do Esp?rito Santo.Center for Health Sciences. Infectious Diseases Unit. Vit?ria, ES, Brazil / Pont?ficia Universidade Cat?lica do Rio Grande do Sul. School of Sciences. Research Group on Biomedical Parasitology...
Performance of an ultra-sensitive assay targeting the circulating anodic antige...
Sousa, Mariana Silva; Dam, Govert J. van; Pinheiro, Marta Cristhiany Cunha; Dood, Claudia J. de; Peralta, Jose Mauro; Peralta, Regina Helena SaramagoTechniques with high sensitivity and specificity are required for an accurate diagnosis in low-transmission settings, where the conventional parasitological methods are insensitive. We determined the accuracy of an up-converting phosphor-lateral flow circulating anodic antigen (UCP-LF CAA) assay in urine and serum for Schistosoma mansoni diagnosis in low-prevalence settings in Ceará, Brazil, before and after pr...
Evaluating a point-of-care circulating cathodic antigen test (POC-CCA) to detec...
Bezerra, Fernando Schemelzer Moraes; Leal, Joames Kauffimann Freitas; Sousa, Mariana Silva; Pinheiro, Marta Cristhiany CunhaSchistosomiasis is still a public health problem in Brazil. The Kato-Katz test is the most frequently used diagnostic method for Schistosoma mansoni infection. However, it lacks sensitivity in areas of low prevalence. We have assessed the positivity rate of S. mansoni infection in Bananeiras, a village on Capistrano, Ceara, Brazil by performing a point-of-care test in urine to determine the circulating cathodic...
Clinical and serological evolution in chronic Chagas disease patients in a 4-ye...
Andrade, Mônica Coelho; Oliveira, Maria de Fátima; Nagao-Dias, Aparecida Tiemi; Coêlho, Ivo Castelo Branco; Bezerra, Fernando Schemelzer MoraesIntroduction: The role of trypanocidal therapy in the chronic phase of Chagas disease remains controversial. Methods: A total of 13 patients with chronic Chagas disease were treated with benznidazole (5mg/kg/day/60 days) and surveyed via antibody measurement and conventional electrocardiogram over the course of 4 years. Results: The antibody titers were signifi cantly reduced after 4 years (p<0.05). Most of the...
Increased detection of schistosomiasis with Kato-Katz and SWAPIgG- ELISA in a N...
Pinheiro, Marta Cristhiany Cunha; Oliveira, Sara Menezes de; Hanemann, Ana Lúcia de Paula; Queiroz, José Ajax NogueiraIntroduction: The laboratory diagnosis of schistosomiasis is based mainly on the detection of parasite eggs in stool samples through the Kato-Katz (KK) technique, reading one slide by test. However, a widely known limitation of parasitological methods is reduced sensitivity, particularly in low endemic areas. Methods: To increase sensitivity, we conducted further slide readings from the same stool sample using ...