8 documents found, page 1 of 1

Antinociceptive and anti-inflammatory activities of the lectin from Marine Red ...

Evidência de dano precoce da cartilagem na osteoartrite experimental por meio d...

Images obtained by scanning electron microscopy of articular cartilage samples from mice submitted to an experimental model of osteoarthritis for semiquantitative analysis.; Imagens obtidas por microscopia eletrônica de varredura de amostras de cartilagem articular de camundongos submetidos a modelo experimental de osteoartrite para análise semiquantitativa.

GABAergic transmission and modulation of anxiety: a review on molecular aspects

Stress responses activate protective mechanisms to achieve homeostasis, but they can be detrimental when such responses become maladaptive. Anxiety relates to risk assessment of a potential threat and involves uncertainty regarding the anticipation of a threatening situation and it dampers quality of life. Gamma-Aminobutyric Acid (GABA) is the major inhibitory system in the central nervous system and plays a ke...

Heme oxygenase-1/biliverdin/carbon monoxide pathway downregulates hypernocicept...

CHAVES, Hellíada Vasconcelos; Objective and design To investigate the role of heme oxygenase-1 (HO-1), carbon monoxide (CO), and biliverdin (BVD) in the zymosan-induced TMJ arthritis in rats. Materials and Methods Mechanical threshold was assessed before and 4 h after TMJ arthritis induction in rats. Cell influx, myeloperoxidase activity, and histological changes were measured in the TMJ lavages and tissues. Tr...

Anti-inflammatory and anti-nociceptive effects of strontium ranelate on the zym...

Background Temporomandibular joint (TMJ) disorders show inflammatory components, heavily impacting on quality of life. Strontium ranelate has previously shown anti-inflammatory and antinociceptive effects on other experimental inflammatory pain models. Thus, we aim to investigate the strontium ranelate efficacy in reducing the zymosan-induced inflammatory hypernociception in the TMJ of rats by evaluating the TN...

Effect of pre-emptive analgesia on clinical parameters and tissue levels of TNF...

This study aimed to evaluate whether pre-emptive analgesia modifies the tissue expression of tumour necrosis factor alpha (TNF-α) and interleukin 1 beta (IL-1β), and whether there is an association with postoperative surgical outcomes. A triple-blind, randomized, placebo-controlled study of patients undergoing mandibular third molar removal was performed. Volunteers were allocated randomly to receive etoricoxib...

Structural features and assessment of zymosan-induced arthritis in rat temporom...

The green seaweed Caulerpa cupressoides var. lycopodium contains three SPs fractions (Cc-SP1, Cc-SP2 and Cc-SP3). Cc-SP1 and Cc-SP2 had anticoagulant (in vitro), pro- and antithrombotic, antinociceptive and/or anti-inflammatory (in vivo) effects. This study analyzed structural features and the antinociceptive and anti-inflammatory effects of Cc-SP1 on zymosan-induced acute arthritis of the rat temporomandibular...

Structural features and assessment of zymosan-induced arthritis in rat temporom...

The green seaweed Caulerpa cupressoides var. lycopodium contains three SPs fractions (Cc-SP1, Cc-SP2 and Cc-SP3). Cc-SP1andCc-SP2 had anticoagulant (in vitro), pro- and antithrombotic, antinociceptive and/or anti-inflammatory (in vivo) effects. This study analyzed structural features and the antinociceptive and anti-inflammatory effects of Cc-SP1 on zymosan-induced acute arthritis of the rat temporomandibular j...