3 documents found, page 1 of 1
Nanoemulsified Butenafine for Enhanced Performance against Experimental Cutaneo...
Bezerra-Souza, Adriana; Jesus, Jéssica A.; Laurenti, Márcia D.; Lalatsa, Aikaterini; Serrano, Dolores R.; Passero, Luiz Felipe D. [UNESP]Made available in DSpace on 2021-06-25T10:58:23Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-01; The production of ergosterol lipid involves the activity of different enzymes and is a crucial event for the Leishmania membrane homeostasis. Such enzymes can be blocked by azoles and allylamines drugs, such as the antifungal butenafine chloride. This drug was active on parasites that cause cutaneous an...
Tolnaftate inhibits ergosterol production and impacts cell viability of Leishma...
Yamamoto, Eduardo Seiji; de Jesus, Jéssica Adriana; Bezerra-Souza, Adriana; Brito, Juliana R.; Lago, João Henrique G.; Laurenti, Márcia DalastraMade available in DSpace on 2020-12-12T02:14:23Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-09-01; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Leishmaniasis is an infectious disease caused by protozoan parasites of the genus Leishmania. The treatment of all forms of leishmaniasis relies on first-line drug, pentav...
The antifungal compound butenafine eliminates promastigote and amastigote forms...
Bezerra-Souza, Adriana; Yamamoto, Eduardo S.; Laurenti, Márcia D.; Ribeiro, Susan P.; Passero, Luiz Felipe D. [UNESP]Made available in DSpace on 2018-12-11T17:06:11Z (GMT). No. of bitstreams: 0 Previous issue date: 2016-12-01; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); The production of ergosterol lipid, important for the Leishmania membrane homeostasis, involves different enzymes. This pathway can be blocked to azoles and allylamines drugs, such as Butenafine. The aim of the present work was to evaluate t...