3 documents found, page 1 of 1
Polyoxometalates as potential next‐generation metallodrugs in the combat agains...
Bijelic, Aleksandar; Aureliano, Manuel; Rompel, AnnettePolyoxometalates (POMs) are an emerging class of inorganic metal oxides, which over the last decades demonstrated promising biological activities by the virtue of their great diversity in structures and properties. They possess high potential for the inhibition of various tumor types; however, their unspecific interactions with biomolecules and toxicity impede their clinical usage. The current focus of the fiel...
The P-type ATPase inhibiting potential of polyoxotungstates.
Gumerova, Nadiia; Krivosudský, Lukáš; Fraqueza, Gil; Breibeck, Joscha; Al-Sayed, Emir; Tanuhadi, Elias; Bijelic, Aleksandar; Fuentes, JuanPolyoxometalates (POMs) are transition metal complexes that exhibit a broad diversity of structures and properties rendering them promising for biological purposes. POMs are able to inhibit a series of biologically important enzymes, including phosphatases, and thus are able to affect many biochemical processes. In the present study, we analyzed and compared the inhibitory effects of nine different polyoxotungs...
The antibacterial activity of polyoxometalates: structures, antibiotic effects ...
Aureliano, M.; Bijelic, Aleksandar; Rompel, AnnettePolyoxometalates (POMs) are, mostly anionic, metal oxide compounds that span a wide range of tunable physical and chemical features rendering them very interesting for biological purposes, an continuously emerging but little explored field. Due to their biological and biochemical effects, including antitumor, -viral and -bacterial properties, POMs and POM-based systems are considered as promising future metallo...