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Allergic asthma exhaled breath metabolome: a challenge for comprehensive two-di...

Caldeira, M.; Perestrelo, Rosa Maria de Sá; Barros, António S.; Bilelo, M. J.; Morête, A.; Câmara, J. S.; Rocha, Sílvia M.

Allergic asthma represents an important public health issue, most common in the paediatric population, characterized by airway inflammation that may lead to changes in volatiles secreted via the lungs. Thus, exhaled breath has potential to be a matrix with relevant metabolomic information to characterize this disease. Progress in biochemistry, health sciences and related areas depends on instrumental advances, ...


Profiling allergic asthma volatile metabolic patterns using a headspace-solid ph...

Caldeira, M.; Barros, António S.; Bilelo, M. J.; Parada, A.; Câmara, J. S.; Rocha, Sílvia M.

Allergicasthmarepresentsanimportantpublichealthissuewithsignificantgrowthovertheyears,especially in the paediatric population. Exhaled breath is a non-invasive, easily performed and rapid method forobtainingsamplesfromthelowerrespiratorytract.Inthepresentmanuscript,themetabolicvolatile profiles of allergic asthma and control children were evaluated by headspace solid-phase microextraction combined with gas chroma...


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