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Proteomic changes in the extracellular environment of sea bass thymocytes expos...

Moreira, Catarina; Hétru, Julie; Paiola, Matthieu; Duflot, Aurélie; Chan, Philippe; Vaudry, David; Monsinjon, Tiphaine; Knigge, Thomas

The thymus is an important immune organ providing the necessary microenvironment for the development of a diverse, self-tolerant T cell repertoire, which is selected to allow for the recognition of foreign antigens while avoiding self-reactivity. Thymus function and activity are known to be regulated by sex steroid hormones, such as oestrogen, leading to sexual dimorphisms in immunocompetence between males and ...


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