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SIRT1 and mTOR interplay in bladder cancer: a potential therapeutic target

Oliveira, P; Silva, AM; Tavares da Silva, E; Jarak, I; Abrantes, M; Botelho, MF; Figueiredo, A; Silva, BM; Pereira, JA; Oliveira, PF; Alves, MG

Date: 2018   |   Origin: Repositório do Centro Hospitalar e Universitário de Coimbra
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Glucose uptake and lipid metabolism are impaired in epicardial adipose tissue f...

Burgeiro, A; Fuhrmann, A; Cherian, S; Espinoza, D; Jarak, I; Carvalho, RA; Loureiro, M; Patrício, M; Antunes, MJ; Carvalho, E

Type 2 diabetes mellitus is a complex metabolic disease, and cardiovascular disease is a leading complication of diabetes. Epicardial adipose tissue surrounding the heart displays biochemical, thermogenic, and cardioprotective properties. However, the metabolic cross-talk between epicardial fat and the myocardium is largely unknown. This study sought to understand epicardial adipose tissue metabolism from heart...

Date: 2016   |   Origin: Repositório do Centro Hospitalar e Universitário de Coimbra
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