12 documents found, page 1 of 2

Epidermal necrolysis: SCORTEN performance in AIDS and non-AIDS patients

Abstract: Background: Stevens-Johnson syndrome and toxic epidermal necrolysis are life-threatening blistering drug reactions with high incidence of ocular sequela. The term ‘Epidermal Necrolysis’ has been recently used to better describe the full spectrum of the disease that includes Stevens-Johnson syndrome and toxic epidermal necrolysis at opposite ends, which differ by the extent of body surface area with ep...

Factors associated with seropositivity for APGL-Iamong household contacts of le...

Abstract: INTRODUCTION: Leprosy is mainly transmitted among family members who share genetic and ambient factors. The clinical form of leprosy in the index case and kinship could be risk factors for leprosy transmission. High antibody levels in household contacts (HC) in the absence of neural or skin lesions may characterize latent infection. This study aimed to evaluate the association between seropositivity f...

Oral coinfection can stress peripheral lymphocyte to inflammatory activity in l...

INTRODUCTION: This study evaluated the intracellular profile of interleukin-2 (IL-2), interleukin-4 (IL-4), interleukin-10 (IL-10) and interferon-γ (IFN-γ) in peripheral blood mononuclear cells (PBMCs) from leprosy patients based on oral infections presence to determine whether these coinfections could be associated with pro-inflammatory activity in leprosy. METHODS: Leprosy patients regardless of clinical form...

The vegetal biomembrane in the healing of chronic venous ulcers

BACKGROUND: The vegetal biomembrane has been used to treat cutaneous ulcers. OBJECTIVES: To assess the role of the vegetal biomembrane on the chronic venous ulcers treatment compared to treatment with collagenase cream. METHODS: Fourteen patients were selected to be treated with vegetal biomembrane and 7 with Fibrase®(CONTROL), followed clinically and photographically by the Wound Healing Index by ImageJ during...

Brazilian blood donation eligibility criteria for dermatologic patients

A focused and commented review on the impact of dermatologic diseases and interventions in the solidary act of donating blood is presented to dermatologists to better advise their patients. This is a review of current Brazilian technical regulations on hemotherapeutic procedures as determined by Ministerial Directive #1353/2011 by the Ministry of Health and current internal regulations of the Hemotherapy Center...

Curativo de biomembrana vegetal e hipersensibilidade

FUNDAMENTOS: A biomembrana vegetal do látex da seringueira Hevea brasiliensis tem sido usada como curativo para úlceras cutâneas. OBJETIVOS: Avaliar a segurança da biomembrana vegetal como curativo em relação à hipersensibilidade ao látex. MÉTODOS: Foram selecionados pacientes com úlceras cutâneas constituindo-se os grupos: controle - baixa exposição profissional ao látex (n=17); alta exposição profissional (n=...

Could leprosy reaction episodes be exacerbated by oral infections?

INTRODUCTION: This study evaluated whether leprosy reactions could be associated with oral infection. METHODS: Leprosy patients (n = 38) with (Group I) and without (Group II) oral infections were selected. Reactions were identified from the clinical and histopathological features associated with serum C-reactive protein (CRP) and10kDa interferon-gamma-induced protein (IP-10) levels, determined before and after ...

Effect of metabolic control on the in vitro proliferation of peripheral blood m...

CONTEXT AND OBJECTIVE: Diabetes mellitus is a clinical syndrome that frequently leads to the development of chronic complications and high susceptibility to infections. It is probably due to defective immunological defense, which may be related to metabolic control of the disease. The aim of this study was to evaluate the effect of metabolic control on immune-cell behavior in type 1 and type 2 diabetic patients...

Úlcera de perna: um estudo de casos em Juiz de Fora-MG (Brasil) e região

FUNDAMENTOS: Úlcera de perna (UP) caracteriza-se por perda do tegumento nas extremidades dos membros inferiores causada geralmente por disfunção vascular. OBJETIVOS: Caracterizar clínica e epidemiologicamente a amostra populacional com UP atendida nos centros de saúde de Juiz de Fora. PACIENTES E MÉTODOS: Submetidos ao protocolo clínico 124 pacientes com UP, de Juiz de Fora e região de janeiro/1999 a agosto/200...

Professor Doutor Luiz Marino Bechelli