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Hyperintense basal ganglia on MR imaging in hematopoietic stem cell transplanta...

Lima,Plínio M.G. de; Piazera,Flávia Z.; Bitencourt,Marco A.; Nunes,Elenaide C.; Morando,Juliane; Fortier,Sérgio C.; Koliski,Adriana; Pasquini,Ricardo

Date: 2011   |   Origin: Oasisbr

Allogeneic bone marrow transplantation for severe aplastic anemia patients with...

Medeiros,Carlos R. de; Coutinho,Elenaide; Carmes,Eliane R.; Bitencourt,Marco A.; Ruiz,Jefferson; Bonfim,Carmen S.; Funke,Vaneusa M.; Setubal,Daniela C.

Hematopoietic progenitor cell transplantation from HLA-identical sibling donors cures 70-90% of Severe Aplastic Anemia (sAA) patients. Older age, heavy exposure to transfusions, immunosuppression treatment (IST) with a long interval from diagnosis to transplant and infection at procedure are associated with poor outcomes. We transplanted 18 patients with sAA and at least one risk factor (RF) for poor prognosis ...

Date: 2008   |   Origin: Oasisbr

Neurological complications of hematopoietic stem cell transplantation (HSCT): a...

Teive,Hélio A.G.; Funke,Vaneuza; Bitencourt,Marco A.; Oliveira,Michel Michels de; Bonfim,Carmen; Zanis-Neto,José; Medeiros,Carlos R. de

We present the neurological complications evaluated in a series of 1000 patients who underwent hematopoietic stem cell transplantation (HSCT). Central nervous system (CNS) neurological complications, particularly brain hemorrhages, were the most common, followed by seizures and CNS infections. An unusual neurological complication was Wernicke's encephalopathy. Less frequent neurological complications were metab...

Date: 2008   |   Origin: Oasisbr

Therapy of chronic myeloid leukemia with imatinib mesylate in Brazil: a study o...

Funke,Vaneuza A. M.; Medeiro,Carlos R.; Lima,Denise H.; Setúbal,Daniela C.; Bitencourt,Marco A.; Bonfim,Carmem M.; Ruiz,Jefferson; Zanis Neto,José

Chronic Myeloid Leukemia (CML) is a clonal disease characterized by balanced translocation between chromosomes 9 and 22 (Philadelphia chromosome). The resulting BCR-ABL gene has tyrosine kinase activity which stimulates cellular growth. Imatinib mesylate is a potent and specific inhibitor of all ABL related kinases. Ninety-eight CML patients were treated with imatinib mesylate from October 2000 to January 2003....

Date: 2005   |   Origin: Oasisbr

Carcinoma de células escamosas em língua pós-transplante de medula óssea por An...

Pasquini,Ricardo; Neto,José Z.; Medeiros,Carlos R.; Bitencourt,Marco A.; Bonfim,Carmem M. S.; Moreira,Vaneuza A.; Setúbal,Daniela C.; Flowers,Mary E. D.

Anemia Fanconi (AF) é uma síndrome autossômica recessiva, caracterizada por pancitopenia progressiva com hipoplasia de MO, em associação com várias anormalidades constitucionais, tendo como único recurso terapêutico com possibilidade potencial de cura o transplante de medula óssea, e sendo tais pacientes propensos ao desenvolvimento de malignidades hematológicas e carcinoma de células escamosas (CEC) em diverso...

Date: 2003   |   Origin: Oasisbr

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