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Risk Factors of Acute T -Cell Mediated and Borderline Rejection Diagnosed in Ea...
Roldão,Marisa; Vida,Ana Carlota; Dias,Joana Monteiro; Vieira,Miguel Bigotte; Magriço,Rita; Silva,Cecília; Caeiro,Fernando; Aires,Inês; Ferreira,AníbalAbstract Introduction: Acute graft rejection remains one of the main causes of graft dysfunction and premature loss. Understanding the factors affecting graft rejection is essential to promote graft survival. Our study aimed to determine the incidence and assess risk factors of acute T‑cell mediated rejection (TCMR) and borderline rejection in early protocol kidney transplant biopsies. Methods: Retrospective si...
The use of hemodialysis in hypercalcemic crisis secondary to primary hyperparat...
Marouço,Catarina Nazário; Caeiro,Fernando; Costa,Bernardo Marques da; Navarro,David; Magriço,Rita; Nolasco,FernandoABSTRACT Severe hypercalcemia can be either acute or decompensate from a chronic state to a medical emergency, the hypercalcemic crisis. The presence of symptoms such as altered mental status or potentially fatal ECG abnormalities demand an expeditious decrease in serum calcium levels. Standard medical therapy consists of vigorous volume replacement, calcitonin and, depending on the etiology, bisphosphonates, c...
Urine volume and residual renal function decline among patients on peritoneal d...
Macau,Ricardo A; Silva,Joana R; Leite,Andreia; Magriço,Rita; Bravo,Pedro; Teixeira e Costa,Fernando; Ramos,AuraIntroduction: Preservation of urine volume and residual renal function in patients on peritoneal dialysis (PD) is a major concern. Some factors have been associated with better prognosis, such as the use of biocompatible solutions, furosemide, or renin-angiotensin-aldosterone system blockers. However, results from previous studies have not been consistent. We thus aimed to study the relation between baseline ch...
Recombinant tissue plasminogen activator plus citrate versus citrate alone as c...
Magriço,Rita; Santos,José Paulo; Colaço,Susana; Dias,Sara; Ramos,AuraIntroduction: The solution used to fill the lumens of the tunnelled catheters for haemodialysis (lock) influences catheter-related complications, such as inadequate blood flow and dialysis efficacy. It is unknown whether a lock strategy with weekly administration of Recombinant Tissue Plasminogen Activator (rt-PA) and of citrate during the remaining dialysis sessions is associated with better catheter blood flo...
Recurrence of anti-factor H associated C3 glomerulonephritis in the kidney allo...
Magriço,Rita; Carvalho,Fernanda; Matos,António Pedro Alves de; Jorge,Cristina; Mateus,Ana; Cruz,Pedro; Oliveira,Carlos; Amoedo,Manuel; Nolasco,FernandoC3 glomerulonephritis is a rare disease defined by deposits of C3 on immunofluorescence due to dysregulation of the alternative pathway of the complement cascade. We present a case of a female patient that presented with nephrotic syndrome at the age of 18 due to C3 glomerulonephritis and progressed to end-stage renal disease after 9 years. She lost the first kidney graft on the third day after transplantation ...
Implications for patients waiting for a kidney transplant of using the calculat...
Magriço,Rita; Malheiro,Jorge; Tafulo,Sandra; Pedroso,Sofia; Almeida,Manuela; ,La Salete; Dias,Leonídio; Castro-Henriques,António; Cabrita,AntónioIntroduction: Kidney transplant improves survival even in highly-sensitized(HS) patients. To overcome their disadvantage in accessing transplantation, those with high Complement Dependent Cytotoxic PRA (CDC-PRA) receive additional points during allocation. Whether this strategy reaches all HS patients and how long they wait for a transplant is largely undetermined. Methods: Patients on our units active wait-li...