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Efficacy and cost-effectiveness of an ACT and compassion-based intervention for...

Trindade, Inês A.; Soares, Andreia; Skvarc, David; Carreiras, Diogo; Pereira, Joana; Lourenço, Óscar; Sampaio, Filipa; Sousa, Bruno de

Breast cancer is the most diagnosed cancer in women worldwide and carries a considerable psychosocial burden. Interventions based on Acceptance and Commitment Therapy (ACT) and compassion-based approaches show promise in improving adjustment and quality of life in people with cancer. The Mind programme is an integrative ACT and compassion-based intervention tailored for women with breast cancer, which aims to p...


Post-COVID-19 condition: where are we now?

Boaventura, Paula; Macedo, Sofia; Ribeiro, Filipa; Jaconiano, Sónia; Soares, Paula

COVID-19 is currently considered a systemic infection involving multiple systems and causing chronic complications. Compared to other post-viral fatigue syndromes, these complications are wider and more intense. The most frequent symptoms are profound fatigue, dyspnea, sleep difficulties, anxiety or depression, reduced lung capacity, memory/cognitive impairment, and hyposmia/anosmia. Risk factors for this condi...


Yoga and Qigong for health: two sides of the same coin?

Boaventura, Paula; Jaconiano, Sónia Isabel Rodrigues Cabral Moraes; Ribeiro, Filipa

Yoga and qigong are ancient mind–body practices used in the East for thousands of years to promote inner peace and mental clarity. Both share breathing techniques and slow movements and are being used as alternative/complementary approaches to the management of disease, especially chronic problems with no effective conventional treatments. However, information comparing the health benefits of both approaches is...


Telomerase promoter mutations in cancer: an emerging molecular biomarker?

Vinagre, João; Pinto, Vasco; Celestino, Ricardo; Reis, Marta; Populo, H; Boaventura, Paula; Melo, Miguel; Catarino, T.; Lima, Jorge; Lopes, José Manuel

Cell immortalization has been considered for a long time as a classic hallmark of cancer cells. Besides telomerase reactivation, such immortalization could be due to telomere maintenance through the “alternative mechanism of telomere lengthening” (ALT) but the mechanisms underlying both forms of reactivation remained elusive. Mutations in the coding region of telomerase gene are very rare in the cancer setting,...


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