Among the unique characteristics associated to gold nanoparticles (AuNPs) in biomedicine, their ability to convert light energy into heat opens ventures for improved cancer therapeutic options, such as photothermal therapy (PTT). PTT relies on the local hyperthermia of tumor cells upon irradiation with light beams, and the association of AuNPs with radiation within the near infrared (NIR) range constitutes an a...
Em meio à globalização e às questões relacionadas ao desenvolvimento sustentável, que impactam diretamente nas políticas sociais e econômicas, as organizações vêm enfrentando desafios e mudanças recorrentes. Sua adaptação e sucesso dependem cada vez mais de suas ações voltadas para a responsabilidade social, o comprometimento organizacional e, principalmente, o papel da cultura organizacional como moderadora ne...
ABSTRACT: The development of active and stable catalytic cathodes is critical for advancing electrochemical carbon dioxide reduction into fuels and chemicals from Lab to market. This is a technology with a high potential to contribute to combat climate changes by using captured CO2, water and renewable energy [1]. The use of pressures higher than atmospheric pressure to carry out the co-electrolysis of CO2 and ...
Background: Designing reliable in vitro assays is crucial to attain impactful results in oncology research. Cell Microarray (CMA) has become a key tool to accelerate cancer research as many samples can be evaluated at the same time in a single slide, allowing the evaluation of many prognostics, diagnostics, and therapy response biomarkers. Previously, we described a model of drug combination using antineoplasti...
ABSTRACT: Electrochemical reduction of carbon dioxide powered by renewable energy to produce fuels and chemicals is a technology with potential to contribute to an economy based on a carbon neutral cycle. The development of cost effective, highly active and stable catalysts for CO2 electroreduction is being intensively researched. This work addresses the development of aerogel supported copper-zinc bimetallic c...
Portugal is one of the most egalitarian countries in Europe in terms of lesbian, gay, bisexual, transgender, and intersex (LGBTI) individuals’ legal rights. However, regarding education Portugal still lacks specific policies, plans and interventions to protect LGBTI students. To assess the perceptions of self-identified LGBTI youth regarding their school context, a total of 663 participants (aged from 15 to 20 ...
Abstract: In this study, titanium dioxide (TiO2) nanostructured films were synthesized under microwave irradiation through low temperature synthesis (80 °C) and integrated in ultraviolet (UV) photodetectors and as photocatalysts. Bacterial nanocellulose (BNC), tracing paper, and polyester film were tested as substrates, since they are inexpensive, flexible, recyclable, lightweight, and when associated to low te...
Rhabdomyolysis (RM) is characterized by acute and often severe skeletal muscle damage resulting in myoglobinuria and, in severe cases, acute renal failure. In adults is typically due to trauma, intoxication or infection, whereas in children is frequently associated with inherited muscle disorders. LPIN1 mutations were identified as a cause of severe recurrent RM, which usually begin in childhood, and infections...
The feasibility of using a zinc oxide rich waste (ZnO>95%), dust originated in the brass smelting industrial process, as a raw material to produce targets to be used in radiofrequency magnetron sputtering (RFMS) deposition of ZnO thin films was investigated. The ZnO waste was characterized in terms of chemical and mineralogical compositions and particle size distribution. The targets were prepared by uniaxial p...
Hybrid lipid–polymer particles are gaining increasing interest to be applied as drug delivery systems due to their greater stability in biological fluids and enhanced cellular uptake of drugs. However, a major drawback is the fact that these particles are usually produced through techniques that use organic solvents. This work studies the possibility of producing for the first time hybrid particles composed by ...