5 documents found, page 1 of 1
A scoping review of the assessment reports of genetic or genomic tests reveals ...
Pezzullo, Angelo Maria; Gris, Angelica Valz; Scarsi, Nicolò; Tona, Diego Maria; Porcelli, Martina; Di Pumpo, Matteo; Piko, Peter; Adany, RozaObjectives: Genetic and genomic tests are the cornerstone of personalized preventive approaches. Inconsistency in evaluating their clinical utility is often cited as a reason for their limited implementation in clinical practice. Previous reviews have primarily focused on theoretical frameworks used for clinical utility evaluations of genetic tests, rather than actual assessments and examined dimensions, rather...
The current stage of Italy in the implementation of genomics into the National ...
Baccolini, Valentina; Pitini, Erica; Galeone, Daniela; Marzuillo, Carolina; Cicchetti, Americo; Arca, Marcello; Vicente, Astrid M.; Boccia, StefaniaIntroduction: Genomics holds significant promise for prevention and clinical care yet integrating it into the national healthcare system (NHS) requires considerable system-wide changes. This study assessed the current stage of Italy in the use of genomics, to map critical areas for improvement and contribute to a strategic plan. Methods: A total of 18 experts rated individually the level of maturity of the Ital...
Implementation of genetic tests for disease prevention: challenges in evidence ...
Gris, Angelica Valz; Vicente, Astrid M.; Boccia, StefaniaExcerpt: Robust evidence supports the critical role of genetic risk in shaping the frequency of a broad range of diseases, underscoring its significance as a determinant of health outcomes [1]. Accordingly, genetic and genomic tests hold significant potential for disease prevention by stratifying populations based on individual genetic profiles and guiding targeted interventions. However, despite the enthusiasm...
Comparative Analysis of Direct Costs of Cancer and Risk Factors in Europe
Herțeliu, Claudiu; Horobeț, Alexandra; Nerău, Vlad; Paraschiv, Anca (Gherman); Ștefan, George; Volintiru, Clara; Zaharia, Rodica Milena; Geantă, MariusThis study explores the direct costs and risk factors associated with cancer across European Union member states, emphasizing the economic and public health implications. A Cancer Risk Factors Index (CRFI) is developed to quantify and compare the impact of various determinants, including obesity, smoking, alcohol consumption, socioeconomic conditions, and pollution. Using data from Eurostat and other authoritat...
The PROPHET project paves the way for personalized prevention in the future hea...
Pastorino, Roberta; Pezzullo, Angelo Maria; Osti, Tommaso; Adany, Roza; Borry, Pascal; Barnhoorn, Floris; Fadil, Eva; Kroese, Mark; Metspalu, AndresNo abstract available