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Updating the OMERACT filter: implications of filter 2.0 to select outcome instr...

Tugwell, P; Boers, M; D'Agostino, MA; Beaton, D; Boonen, A; Bingham, CO; Choy, E; Conaghan, PG; Dougados, M; Duarte, C; Furst, DE; Guillemin, F

OBJECTIVE: The Outcome Measures in Rheumatology (OMERACT) Filter provides guidelines for the development and validation of outcome measures for use in clinical research. The "Truth" section of the OMERACT Filter requires that criteria be met to demonstrate that the outcome instrument meets the criteria for content, face, and construct validity. METHODS: Discussion groups critically reviewed a variety of ways in...


EULAR evidence-based recommendations on the management of systemic glucocortico...

Hoes, JN; Jacobs, JW; Boers, M; Boumpas, D; Buttgereit, F; Caeyers, N; Choy, EH; Pereira da Silva, JA

OBJECTIVE: To develop evidence-based recommendations for the management of systemic glucocorticoid (GC) therapy in rheumatic diseases. METHODS: The multidisciplinary guideline development group from 11 European countries, Canada and the USA consisted of 15 rheumatologists, 1 internist, 1 rheumatologist-epidemiologist, 1 health professional, 1 patient and 1 research fellow. The Delphi method was used to agree on...


Safety of low dose glucocorticoid treatment in rheumatoid arthritis: published ...

Pereira da Silva, JA; Jacobs, JW; Kirwan, JR; Boers, M; Saag, KG; Inês, L; Koning, EJ

Adverse effects of glucocorticoids have been abundantly reported. Published reports on low dose glucocorticoid treatment show that few of the commonly held beliefs about their incidence, prevalence, and impact are supported by clear scientific evidence. Safety data from recent randomised controlled clinical trials of low dose glucocorticoid treatment in RA suggest that adverse effects associated with this drug ...


Low-dose glucocorticoid therapy in rheumatoid arthritis. A review on safety: pu...

Pereira da Silva, JA; Jacobs, JW; Kirwan, JR; Boers, M; Saag, KG; Inês, L; Koning, EJ


Standardised nomenclature for glucocorticoid dosages and glucocorticoid treatme...

Buttgereit, F; Pereira da Silva, JA; Boers, M; Burmester, GR; Cutolo, M; Jacobs, J; Kirwan, J

In rheumatology and other medical specialties there is a discrepancy between the widespread use and the imprecise designation of glucocorticoid treatment regimens. Verbal descriptions of glucocorticoid treatment regimens used in various phases of diseases vary between countries and institutions. Given this background, a workshop under the auspices of the EULAR Standing Committee on International Clinical Studie...


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