5 documents found, page 1 of 1
Central Diabetes Insipidus Following Immunization With BNT162b2 mRNA COVID-19 V...
Bouça, B; Roldão, M; Bogalho, P; Cerqueira, L; Silva-Nunes, JIntroduction: Cases of central diabetes insipidus (CDI) have been reported after COVID-19 infection, with hypophysitis being the most likely cause. COVID-19 vaccines potential adverse effects may mimetize some of these complications. Case report: Woman 37 years old, with rheumatoid arthritis under adalimumab (40 mg twice a month) since December 2018. She was in her usual state of health when she has received th...
The Role of the Metabolome and Non-Coding RNA on Pheochromocytomas and Paragang...
Bouça, B; Bogalho, P; Rizzo, M; Silva-Nunes, JPheochromocytoma and paragangliomas (PPGL) are rare neuroendocrine tumors. In some patients they exhibit malignant behavior characterized by the presence of metastases, limiting treatment options and survival rates. Therapeutic options are limited to surgery, localized radiotherapy, and a few systemic therapies. However, in several recent studies, non-coding RNA molecules are gaining increasing attention as mar...
Peptide Receptor Radionuclide Therapy with 177 Lu-DOTA-TATE As a Promising Trea...
Magalhães, D; Sampaio, I; Ferreira, G; Bogalho, P; Martins-Branco, D; Santos, R; Duarte, HIntroduction: Insulinomas are a rare type of pancreatic neuroendocrine tumours characterized by insulin hypersecretion. They are considered malignant when metastases are present. Traditional therapies often promote only temporarily symptomatic relief and may be associated with severe adverse effects. There is scarce experience in treating malignant insulinomas with peptide receptors radionuclide therapy (PRRNT)...
Lipid disorders in children with insulin-dependent diabetes mellitus.
Bogalho, PLipid and lipoprotein disorders are frequently detected in insulin dependent diabetics, which predisposes the high cardiovascular risk present in these patients. Studies performed with insulin dependent children showed early changes in lipid metabolism, usually correlated and aggravated by poor glycemic control. However, there are abnormalities present even in diabetic children with good glycemic control. The u...
Distúrbios Lipídicos em Crianças com Diabetes Mellitus Insulino-Dependentes
Bogalho, POs distúrbios dos lípidos e das lipoproteínas plasmáticas, frequentes em doentes diabéticos insulinodependentes, contribuem significativamente para o risco cardiovascular elevado que estes indivíduos apresentam. Estudos efectuados em crianças e jovens insulinodependentes, demonstram o aparecimento precoce de alterações no metabolismo lipídico, habitualmente associa das e agravadas por um deficiente controle gli...