4 documents found, page 1 of 1
Acrocomia aculeata associated with doxorubicin: cardioprotection and anticancer...
Monteiro-Alfredo, Tamaeh; Dos Santos, Jéssica Maurino; Antunes, Kátia Ávila; Cunha, Janielle; da Silva Baldivia, Debora; Pires, Ana SaloméDoxorubicin (Dox) is a chemotherapeutic agent widely used in the clinic, whose side effects include cardiotoxicity, associated with decreased antioxidant defenses and increased oxidative stress. The association of Dox with natural antioxidants can extend its use if not interfering with its pharmacological potential. In this study, we aimed to understand the effects and mechanisms of the aqueous extract of Acroc...
Dietary supplementation with Camu-camu and continuous exercises in the treatmen...
Nascimento, Ozanildo Vilaça do; Boleti, Ana Paula de Araújo; Schwertz, Maíra Cássia; Lima, Emerson SilvaObjective The goal of this study were to investigate the effects of continuous exercise with/or without the ingestion the Camu-camu pulp in a rat model of obesity. Methods Neonate male Wistar rats, receiving monosodium glutamate, subcutaneously were separated into foour groups: sedentary group S (no treatment), exercise group E (continuous swimming training), Camu-camu group C (25mL of pulp of Camu-camu/day) an...
In vitro and in vivo anti-malarial activity of plants from the Brazilian Amazon
Lima, Renata Braga Souza; Rocha Silva, Luiz F.; Melo, Márcia R.S.; Costa, Jacqueline S.; Picanço, Neila Soares; Lima, Emerson SilvaBackground: The anti-malarials quinine and artemisinin were isolated from traditionally used plants (Cinchona spp. and Artemisia annua, respectively). The synthetic quinoline anti-malarials (e.g. chloroquine) and semi-synthetic artemisinin derivatives (e.g. artesunate) were developed based on these natural products. Malaria is endemic to the Amazon region where Plasmodium falciparum and Plasmodium vivax drug-re...
Microbiological quality, chemical profile as well as antioxidant and antidiabet...
Rocha, Paola dos Santos; Boleti, Ana Paula de Araújo; Vieira, Maria do Carmo; Carollo, Carlos Alexandre; Silva, Denise Brentan; Estevinho, Leticia M.Schinus terebinthifolius Raddi, commonly known as Brazilian peppertree, is a plant species widely used in Brazilian traditional medicine for various purposes. The objective of this study was to assess the microbiological quality, safety, chemical profile as well as antioxidant and antidiabetic potentials of different parts of S. terebinthifolius. Microbiological analysis of the methanolic extracts of the roots ...