2 documents found, page 1 of 1
The conserved genetic program of male germ cells uncovers ancient regulators of...
Brattig-Correia, Rion; Almeida, Joana M.; Wyrwoll, Margot Julia; Julca, Irene; Sobral, Daniel; Misra, Chandra Shekhar; Di Persio, SaraNational Institutes of Health (1R01LM012832) National Science Foundation (Research Traineeship grant 1735095). Deutsche Forschungsgemeinschaft (329621271). Ministry of Education, Singapore (MOE2018-T2-2-053). Publisher Copyright: © 2024, Brattig-Correia, Almeida, Wyrwoll et al.; Male germ cells share a common origin across animal species, therefore they likely retain a conserved genetic program that defines the...
Detection of atovaquone-proguanil resistance conferring mutations in Plasmodium...
Pimentel, Sónia; Nogueira, Fátima; Benchimol, Carla; Quinhentos, Vatúsia; Bom, Joana; Varandas, Luís; Do Rosário, Virgílio; Bernardino, LuísBackground: The fixed dose combination atovaquone-proguanil is a recently introduced antimalarial for treatment and prophylaxis of Plasmodium falciparum malaria. It is highly effective with a good tolerability profile and a convenient prophylactic regimen. Nevertheless, cases of treatment failure have already been reported, which have been associated to mutations in the cytochrome b gene of the Plasmodium (pfcy...