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Synthesis and cytotoxic evaluation of a series of 2-amino-naphthoquinones again...

Moraes, Thiago A. P. de; S. Filha, Maria J.; Camara, Celso A.; Silva, Tania M. S.; Soares, Bruno M.; Bomfim, Igor S.; Pessoa, Claudia

The cytotoxicity of a series of aminonaphthoquinones resulting from the reaction of suitable aminoacids with 1,4-naphthoquinone was assayed against SF-295 (glioblastoma), MDAMB-435 (breast), HCT-8 (colon), HCT-116 (colon), HL-60 (leukemia), OVCAR-8 (ovarian), NCI-H358M (bronchoalveolar lung carcinoma) and PC3-M (prostate) cancer cells and also against PBMC (peripheral blood mononuclear cells). The results demon...

Date: 2014 | Origin: Oasisbr

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