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Gellan gum/pectin beads are safe and efficient for the targeted colonic deliver...

Prezotti, F; Boni, F; Ferreira, N; Souza e Silva, D; Campana-Filho, S; Almeida, A; Vasconcelos, T; Gremião, M; Cury, B; Sarmento, B

This work addresses the establishment and characterization of gellan gum:pectin (GG:P) biodegradable mucoadhesive beads intended for the colon-targeted delivery of resveratrol (RES). The impact of the polymer carrier system on the cytotoxicity and permeability of RES was evaluated. Beads of circular shape (circularity index of 0.81) with an average diameter of 914 µm, Span index of 0.29, and RES entrapment effi...

Date: 2018   |   Origin: Repositório Aberto da Universidade do Porto
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