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Detection and quantification of EGFR T790M mutation in liquid biopsies by dropl...
Silveira, Catarina; Sousa, Ana Carla; Janeiro, André; Malveiro, Sara; Teixeira, Encarnação; Brysch, Eva; Pantarotto, Marcos; Felizardo, MargaridaBackground: Liquid biopsy allows the identification of targetable cancer mutations in a minimally invasive manner. In patients with advanced non-small cell lung cancer (NSCLC), droplet digital PCR (ddPCR) is increasingly used to genotype the epidermal growth factor receptor (EGFR) gene in circulating cell-free DNA (cfDNA). However, the sensitivity of this method is still under debate. The aim of this study was ...
Influence of a specific exercise program in the institutionalized elderly balance
Guimarães, Cátia; Ferreira, Margarida; Santos, Paula Clara; Saavedra, MarianaTo determinate the effectiveness of a specific exercise program on balance and functional capacity of the daily activities of institutionalized elderl
Pulmonary Tuberculosis Reactivation: Triggered by the Descent in Altitude?
Bianchi-de-Aguiar, Filipa; Campanha, Rafaela; Guimarães, Cátia; Simões-Raposo, MargaridaHigh altitudes are linked to decreased rates of pulmonary tuberculosis infection, disease and mortality. However, its relevance as a trigger for pulmonary tuberculosis reactivation in immunocompetent patients is not documented. A 28-year-old healthy Nepalese female was admitted in the emergency department with sudden left pleuritic back pain with shortness of breath, two weeks after arriving in Lisbon, having a...
Information in movement: production and organization of knowledge in social spaces
Marteleto, Regina Maria; Ribeiro, Leila Beatriz; Guimarães, CátiaKnowledge, information and communication build the paradigm of the structure and functioning of the contemporary societies. Assuming the presupposition that knowledge is always conceptualized by the conditions that make it possible, and that it advances while transforming these conditions, as the non governmental organiza-tions, as spaces of knowledge production, organization and innovation. Sceneries of symbol...