5 documents found, page 1 of 1
Biodegradable nanoparticles for the treatment of epilepsy: From current advance...
Bonilla, Lorena; Esteruelas, Gerard; Ettcheto, Miren; Espina, Marta; García, María Luisa; Camins, Antoni; Souto, Eliana B.; Cano, AmandaEpilepsy is the second most prevalent neurological disease worldwide. It is mainly characterized by an electrical abnormal activity in different brain regions. The massive entrance of Ca2+ into neurons is the main neurotoxic process that lead to cell death and finally to neurodegeneration. Although there are a huge number of antiseizure medications, there are many patients who do not respond to the treatments a...
Lipid nanoparticles for the posterior eye segment
Bonilla, Lorena; Espina, Marta; Severino, Patricia; Cano, Amanda; Ettcheto, Miren; Camins, Antoni; García, Maria Luisa; Souto, Eliana B.This review highlights the application of lipid nanoparticles (Solid Lipid Nanoparticles, Nanostructured Lipid Carriers, or Lipid Drug Conjugates) as effective drug carriers for pathologies affecting the posterior ocular segment. Eye anatomy and the most relevant diseases affecting the posterior segment will be summarized. Moreover, preparation methods and different types and subtypes of lipid nanoparticles wil...
Biodegradable nanoparticles for the treatment of epilepsy: from current advance...
Bonilla, Lorena; Esteruelas, Gerard; Ettcheto, Miren; Espina, Marta; García, María Luisa; Camins, Antoni; Souto, Eliana B.; Cano, AmandaEpilepsy is the second most prevalent neurological disease worldwide. It is mainly characterized by an electrical abnormal activity in different brain regions. The massive entrance of Ca2+ into neurons is the main neurotoxic process that lead to cell death and finally to neurodegeneration. Although there are a huge number of antiseizure medications, there are many patients who do not respond to the treatments a...
Metal-Based Nanoparticles as Antimicrobial Agents: An Overview
Sánchez-López, Elena; Gomes, Daniela; Esteruelas, Gerard; Bonilla, Lorena; Lopez-Machado, Ana Laura; Galindo, Ruth; Cano, Amanda; Espina, MartaMetal-based nanoparticles have been extensively investigated for a set of biomedical applications. According to the World Health Organization, in addition to their reduced size and selectivity for bacteria, metal-based nanoparticles have also proved to be effective against pathogens listed as a priority. Metal-based nanoparticles are known to have non-specific bacterial toxicity mechanisms (they do not bind to ...
Metal-based nanoparticles as antimicrobial agents: an overview
Sánchez-López, Elena; Gomes, Daniela; Esteruelas, Gerard; Bonilla, Lorena; Lopez-Machado, Ana Laura; Galindo, Ruth; Cano, Amanda; Espina, MartaMetal-based nanoparticles have been extensively investigated for a set of biomedical applications. According to the World Health Organization, in addition to their reduced size and selectivity for bacteria, metal-based nanoparticles have also proved to be effective against pathogens listed as a priority. Metal-based nanoparticles are known to have non-specific bacterial toxicity mechanisms (they do not bind to ...