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Prevalence and spectrum of Nkx2.5 mutations associated with idiopathic atrial f...

Xie, Wen-Hui; Chang, Cheng; Xu, Ying-Jia; Li, Ruo-Gu; Qu, Xin-Kai; Fang, Wei-Yi; Liu, Xu; Yang, Yi-Qing

OBJECTIVE: The aim of this study was to evaluate the prevalence and spectrum of Nkx2.5 mutations associated with idiopathic atrial fibrillation (AF). METHODS: A cohort of 136 unrelated patients with idiopathic atrial fibrillation and 200 unrelated, ethnically matched healthy controls were enrolled. The coding exons and splice junctions of the Nkx2.5 gene were sequenced in 136 atrial fibrillation patients, and t...

Date: 2013   |   Origin: Oasisbr
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