27 documents found, page 1 of 3
Caregiver perceptions of the impact and effect of family conferences for patien...
Nascimento, Ana; Brandão-Silva, Joana; Cunha, Daniela; Ramos, Iliana; Pereira, Cristina; Semedo, Valéria; Andrade, José Paulo; Rocha-Neves, JoãoIntroduction: Family conferences (FC) are a structured and therapeutic tool in palliative care, promoting effective communication between the healthcare team, patient and family. They are especially relevant for patients with high clinical complexity, both in hospital settings and in primary care. Objective: To evaluate caregivers’ perceptions of the impact of FC on patients cared for by palliative care teams a...
Palliative care literacy assessment in non-health professionals
Coimbra, Mariana; Dixe, Maria dos Anjos; Neves Tavares, Pedro; Dourado, MaríliaIntroduction: Health literacy is becoming increasingly important in health policies worldwide. It is crucial to develop tools to measure literacy levels in palliative care. Objectives: The main objective was to determine the level of knowledge of non-health professionals regarding palliative care. As a secondary objective, we aimed to develop and validate a tool to measure palliative care literacy among non-hea...
The Debate between the Human Microbiota and Immune System in Treating Aerodiges...
Domingues, Cátia; Cabral, Cristiana Isabel Lima; Jarak, Ivana; Veiga, Francisco; Dourado, Marília; Figueiras, AnaThe human microbiota comprises a group of microorganisms co-existing in the human body. Unbalanced microbiota homeostasis may impact metabolic and immune system regulation, shrinking the edge between health and disease. Recently, the microbiota has been considered a prominent extrinsic/intrinsic element of cancer development and a promising milestone in the modulation of conventional cancer treatments. Particul...
Platelet Membrane Proteins as Pain Biomarkers in Patients with Severe Dementia
Ribeiro, Hugo; Alves, Raquel; Jorge, Joana; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana Bela; Veríssimo, Manuel T.; Dourado, MaríliaPain is one of the most frequent health problems, and its evaluation and therapeutic approach largely depend on patient self-report. When it is not possible to obtain a self-report, the therapeutic decision becomes more difficult and limited. This study aims to evaluate whether some membrane platelet proteins could be of value in pain characterization. To achieve this goal, we used 53 blood samples obtained fro...
Opioids and constipation therapy in the last week of life: Their impact on pati...
Ribeiro, Hugo; Magalhães, Júlia; Cardoso, Tatiana; Chaves-Castro, Isabel; Lopes-Mota, Carla; Costa, Elisabete; Rocha, Patrícia da; Lopes, LuísaThe use of opioids to control pain at the end of life may cause constipation, a symptom that can negatively influence the well-being of patients and caregivers. The main aim of this study was to evaluate the impact of constipation on symptomatic control and patients' overall quality of life at this stage. A particular focus was placed on opioids. We also intended to investigate whether constipation and caregive...
Monocytes in the Characterization of Pain in Palliative Patients with Severe De...
Ribeiro, Hugo; Alves, Raquel; Jorge, Joana; Gonçalves, Ana Cristina; Sarmento-Ribeiro, Ana Bela; Veríssimo, Manuel T.; Andrade, José PauloIn assessing and managing pain, when obtaining a self-report is impossible, therapeutic decision-making becomes more challenging. This study aimed to investigate whether monocytes and some membrane monocyte proteins, identified as a cluster of differentiation (CD), could be potential non-invasive peripheral biomarkers in identifying and characterizing pain in patients with severe dementia. We used 53 blood samp...
Pediatric Drug Development: Reviewing Challenges and Opportunities by Tracking ...
Domingues, Cátia; Jarak, Ivana; Veiga, Francisco; Dourado, Marília; Figueiras, AnaThe paradigm of pediatric drug development has been evolving in a "carrot-and-stick"-based tactic to address population-specific issues. However, the off-label prescription of adult medicines to pediatric patients remains a feature of clinical practice, which may compromise the age-appropriate evaluation of treatments. Therefore, the United States and the European Pediatric Formulation Initiative have recommend...
Non-steroidal anti-inflammatory drugs (NSAIDs), pain and aging: Adjusting presc...
Ribeiro, Hugo; Rodrigues, Inês; Napoleão, Leonardo; Lira, Luís; Marques, Denise; Veríssimo, Manuel T.; Andrade, José Paulo; Dourado, MaríliaA narrative review of papers published from January 2011 to December 2021, after a literature search in selected databases using the terms "pharmacokinetics", "ibuprofen", "diclofenac", "acemetacin", "naproxen", "etodolac" and "etoricoxib" was performed. From 828 articles identified, only eight met the inclusion criteria. Selective COX-2 inhibitors are associated with higher cardiovascular risk, while non-selec...
Prescription trends at the end of life in a palliative care unit: observational...
Peralta, Tatiana; Castel-Branco, Maria Margarida; Reis-Pina, Paulo; Figueiredo, Isabel Vitória; Dourado, MaríliaBackground: Symptomatic control is essential in palliative care, particularly in end‑of‑life, in which the pathophysiological changes that characterize this last phase of life strengthen the need to carry out an early therapeutic review. Hence, we aim to evaluate the prescribing pattern at a palliative care unit at two different time points: on admission and the day of the patient’s death. Methods: Quantitative...
Signs and symptoms in Integrated Continuous Care Units: a study in two medium-t...
Armindo, Raquel Maria; Dourado, MaríliaObjectives: To characterize the socio-demographic profile, signs, and symptoms of patients admitted to Medium-Term and Rehabilitation Units (UMDR) of the National Integrated Continuing Care Network, and to reflect on the appropriateness of the referral to these units. Methods: A quantitative, descriptive, cross-sectional, observational, and retrospective study was carried out in two UMDRs in the district of Lei...