10 documents found, page 1 of 1
Acute Genital Ulcer in a Young Girl
Rato, Margarida; Borges, Ana Sofia; Rodrigues, Ana; Fernandes, Cândida.; .
Congenital Ichthyoses: 11 Cases from the Pediatric Dermatology Multidisciplinar...
Borges, Ana Sofia; Cordeiro, A.; Brasileiro, Ana; Paiva Lopes, Maria JoãoIntroduction: Congenital ichthyoses are a heterogeneous group of hereditary genetic disorders that occur due to a defective keratinization and consequent disruption of the skin barrier function. Although rare, they are presented as a diagnostic and therapeutic challenge. This study aimed to characterize clinically and genotypically the cases of non-syndromic congenital ichthyoses and to evaluate possible genoty...
Topical Immunomodulation with Diphenlycyclopropenone for Alopecia Areata
Borges, Ana Sofia; Brasileiro, Ana; Ramos Pinheiro, Rita; Lencastre, AndréIntroduction: Topical immunotherapy with diphenylcyclopropenone is a treatment option for patients with refractory or extensive alopecia areata. The aim of this study was to evaluate the clinical efficacy and tolerability of diphenylcyclopropenone therapy, in patients with alopecia areata, and identify possible prognostic factors that predict response to treatment. Methods: We conducted a retrospective study th...
Facial Lesions in Children: Often a Challenging Diagnosis
Borges, Ana Sofia; Brasileiro, A.; Matos Pires, E.; Baptista, J.; Galhardas, C.; Apetato, M..; .
Sexually Transmitted Infections in Men Aged 50 Years and Older in a Sexual Tran...
Borges, Ana Sofia; Rato, Margarida; Brasileiro, Ana; Fernandes, Cândida; Rodrigues, AnaIntroduction: Sexually transmitted infections (STIs) are a significant public health problem worldwide. They are more frequent in young men; however the prevalence in older individuals is increasing. The aim of this study was to access the prevalence of STIs diagnosis in men aged 50 years and older. We also aimed to compare the demographic and behavioral characteristics of those diagnosed with STIs and those wi...
Melatonin and Atopic Dermatitis: New Insights in Pathophysiology and its Role i...
Borges, Ana Sofia; Brasileiro, A.; Mendes-Bastos, P.Sleep disturbance is common in children with atopic dermatitis, with a significant impact in their quality of life and negative effects on behavior and neurocognitive function. However, the pathophysiology of sleep disturbance in patients with atopic dermatitis is not well understood. It was thought to be consequence of pruritus and scratching, but nowadays we know to a consequence of multiple factors. Recent s...
Whistle stability and variation in captive bottlenose dolphins (Tursiops trunca...
Lopes, Patrícia Alexandra Rachinas; Luís, Ana Rita; Borges, Ana Sofia; Neto, Márcia P.; Santos, Manuel Eduardo dosCommon bottlenose dolphins (Tursiops trunca-tus) produce a range of underwater vocalizations, both pulsed (echolocation clicks and burst-pulses) and nonpulsed (whistles). Whistles may be emit-ted in stereotyped (signature) or variant patterns, and their production might be affected by sex, age, environmental, and social contexts. This study examined, non-intrusively, the whistle emissions of six captive bottlen...
Mucosal and Periungual Telangiectasia as Signs of Systemic Disease
Borges, Ana Sofia; Campos, Sara; Brasileiro, AnaN/A.
Dermite Atópica: Os Novos Conhecimentos Sobre a Fisiopatologia da Doença
Borges, Ana Sofia; Pinheiro, Rita; Brasileiro, AnaA dermite atópica é uma doença inflamatória crónica caraterizada por intenso prurido e lesões eczematosas recorrentes. Observa-se com maior frequência em crianças com história pessoal e/ou familiar de atopia, porém também ocorre na idade adulta. Embora anteriormente pensada como uma doença desencadeada por uma resposta imunitária Th2 inapropriada, estudos recentes têm demonstrado que a disfunção da barreira cut...
Treatment implications of New Physiopathology Insights in Atopic Dermatitis
Borges, Ana Sofia; Pinheiro, Rita; Brasileiro, AnaAtopic dermatitis is a chronic inflammatory skin disease that usually affects children, but can also start in adults. This disease has a strong impact on the quality of life, however treatment options for severe atopic dermatitis are scarce. New insights into the physiopathology, emphasizing the crucial role of epidermal barrier dysfunction and its relationship with immune dysregulation, contributed to the deve...