4 documents found, page 1 of 1
Warfarin hipersensitivity: how to deal with it?.
Lima, Ana Furtado; Reis, José; Serrano, Fátima; Borges, AugustaThe authors report a clinical case of warfarin hypersensitivity noticed when a patient, with thromboembolic risk, was submitted to warfarin. She was found to be heterozigotic to -1639G>A (gene VKORC1) and homozygotic to 1075A>C (genotype CYP2C9*3/*3). In this article the warfarin pharmacodinamics and its role over Vitamin K is revisited. It includes some suggested indications for investigating genetic polymorph...
Kidney abscess during pregnancy. A case report.
Santos, Leonor; Borges, Augusta; Serrano, Fátima; Alves, Maria José; Campos, AnaThe development of a kidney abscess is extremely rare despite the fact that urinary tract infections are quite common during pregnancy. The pathogenesis of renal abscess has changed over the years. Nowadays, more than 75% of the renal abscess arises from a previous urinary tract infection. The authors report the case of a 35 year-old woman, pregnant, with fever, nausea, vomits, right lumbar tenderness, admitted...
Cerebral malaria and post-malarial neurological syndrome
Sambo, Maria do Rosário; Borges, Augusta; Borges, FernandoThe cerebral form of severe Plasmodium falciparum malaria is the commonnest and most important of the many neurologícal manifestations and complicatíons of malaria. The purpose of this article is to review, in some detail, our knowledge of cerebral malaria. By definition, cerebral malaria requires coma to persist for at least 30 minutes, alter a generalized convulsion, to make the distinction from transient pos...
Renal failure and the internist - Clinical and laboratorial management
Borges, Augusta; Aragão, Teresa; Mello e Silva, Alberto; Borges, Fernando; Sousa Uva, LuísA physician's approach to renalfailure should always be multifactoriaL It is important to establish a differential diagnosis as regards the various types of renal failure and to differentiate between an intrinsic renal lesion and multisys tem disorder. The initial approach should be non invasive and consist of a careful clinical history and examination, the analysis of the urinary sediment and the renal ult...