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An Uncommon Cause of Recurrent Dysphagia and Chest Pain in an Adolescent Boy

Craveiro Costa, R; Patena Forte, J; Correia, M; Borges, C; Faria, H

An 11-year-old boy was brought to the emergency department with a week-long history of widespread pain in his upper abdomen that worsened with deep breathing and eating, sialorrhea, food impaction sensation, and a recent fever. Ten months prior, he had similar symptoms and was diagnosed with a pharyngeal phlegmon. He was treated with antibiotics and dexamethasone. In the current episode, he presented with mild ...

Date: 2024   |   Origin: Saúde - CUF

Exposure Scenarios for Estimating Contaminant Levels in Healthy Sustainable Die...

Ramos, H; Reis-Mendes, A; Silva, M; Ribeiro, M; Araújo, AM; Borges, C; Viegas, Olga; Melo, A; Martins, Z; Faria, MA; Ferreira, IMPLVO

<jats:p>Consumers are regularly exposed to well-known food contaminants (FCs), which are typically assessed for risk on an individual basis. However, there is limited knowledge about the overall levels and combinations of these compounds depending on dietary choices. The goal of this study was to estimate the real-life mixtures of FCs in different dietary models by integrating extensive data from the scientific...


Cd44v6 high membranous expression is a predictive marker of therapy response in...

Almeida, GM; Pereira, C; Park, JH; Lemos, C; Campelos, S; Gullo, I; Martins, D; Gonçalves, G; Leitão, D; Neto, JL; André, A; Borges, C; Almeida, D

In gastric cancer (GC), biomarkers that define prognosis and predict treatment response remain scarce. We hypothesized that the extent of CD44v6 membranous tumor expression could predict prognosis and therapy response in GC patients. Two GC surgical cohorts, from Portugal and South Korea (n = 964), were characterized for the extension of CD44v6 membranous immuno-expression, clinicopathological features, patient...


Primary Hyperoxaluria type 1 – Two Case Reports

Ganhão, I; Borges, C; Amorim, M; Braga da Cruz, M; Nobre, S; Francisco, T; Cardoso, D; Abranches, M

Primary hyperoxaluria type 1 is a rare autosomal recessive inherited disease, caused by mutations in AGXT gene, with an estimated incidence of 1:100.000 live births per year in Europe. Over 50% present with end stage renal disease at diagnosis. Case reports: The first case is a 14‑year‑old boy, second child to consanguineous parents, with history of recurrent lithiasis and ureteral dilatation starting 5 years b...


Doença de arranhadela do gato em adolescente - uma apresentação atípica

Pereira, M; Carneiro, S; Braz, M; Bacalhau, S; Borges, C; Neto, A

Date: 2018   |   Origin: Saúde - CUF

Plasma exchange in severe acute relapses of multiple sclerosis - Results from a...

Correia, I; Ribeiro, JJ; Isidoro, L; Batista, S; Nunes, C; Macário, C; Borges, C; Tomaz, J; Sousa, L

Relapses in Multiple Sclerosis (MS) are often associated with significant disability impairment which is resultant from poor response to corticosteroids. In such severe cases, plasma exchange (PLEX) may be used, although only a few studies with MS patients have been reported. Our objective was to evaluate the effectiveness of PLEX in severe relapses of MS. METHODS: Retrospective study of MS patients treated wit...


Osteomielite Crónica em Lactente

Painho, T; Borges, C; Varandas, L; Tavares, D; Gouveia, C


Multiple Haemangiomas, Diaphragmatic Eventration and Beckwith-Wiedemann Syndrom...

Francisco, T; Gonçalves, RM; Borges, C; Neto, MT

A 6-month-old girl with Beckwith-Wiedemann syndrome, multiple haemangiomas (axillary, laryngeal, pulmonary and hepatic) and diaphragmatic eventration was reported. All tumours responded to treatment with propranolol. The surgical correction of diaphragmatic eventration was crucial to a better outcome.


Vólvulo Intestinal en el Periodo Neonatal: 8 Años de Experiencia en un Hospital...

Silva, A; Freitas, F; Knoblich, M; Borges, C; Neto, MT; Serelha, M; Casella, P

Análise dos casos de volvo intestinal ocorridos no período neonatal nos últimos 8 anos (2002 a 2010). Material e métodos: Foram estudados os recém-nascidos admitidos na UCIN cujo diagnóstico de saída foi volvo intestinal. Foram estudados os seguintes parâmetros: idade gestacional e pós-natal, apresentação clínica e imagiológica, intervenção cirúrgica e resultados. Resultados: Foram identificados 15 doentes 7 do...


Bioactivity studies and chemical profile of the antidiabetic plant Genista tenera

Rauter, A. P.; Martins, F.; Lopes, R.; Ferreira, J.; Serralheiro, L. M; Araújo, M. E.; Borges, C; Justino, Jorge; V.M. Silva, Filipa; Goulart, Margarida

Aim of the study: Genista tenera is a plant endemic to the island of Madeira and is used in folk medicine to control diabetes. In the present work we evaluate the antihyperglycaemic activity of its n-butanol extract and determine its chromatographic profile. In addition, this extract, the ethyl acetate and diethyl ether plant extracts were studied in order to assess the plant antioxidant and acetylcholinesteras...


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