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Tribological properties of antimicrobial surfaces for orthopaedics and oral reh...

Veloso, J.; Borges, J.; Vaz, F.; Carvalho, O.; Souza, J. C. M.; Gomes, J. R.

Inflammatory reactions around implants and prosthetics can occur due to the accumulation of pathogenic bacteria species. The long-term success of implants and prostheses depends on the healthy state of surrounding mucosa, bone, and connective tissues, that can be controlled by manufacturing surfaces with specific physical-chemical aspects to prevent the accumulation of bacteria. Among several properties, the fr...


Testing a methodology based on ALS data and diameter distribution simulation to...

Magalhães, J.; Guerra Hernández, J.; Cosenza, D.; Marques, S.; Borges, J.; Tomé, M.


Muography in the university and in the museum

Afonso, L.; Alexandre, I.; Andringa, S.; Assis, P.; Blanco, O.; Bezzeghoud, M.; Borges, J.; Caldeira, B.; Cazon, L.; Costa, J.; Dobrilla, P.; Duarte, M.

The LouMu team joins together specialists in particle detectors and in cosmic ray analyses, geophysicists and science communicators to muograph an underground gallery of an old mine, now open to visitors of a science museum. The muon telescope is made of Resistive Plate Chambers (RPCs) developed to operate stably and with low consumption at remote locations, and it has been tested in the Coimbra University, bef...


GPR Clutter Reflection Noise-Filtering through Singular Value Decomposition in ...

Oliveira, R. J.; Caldeira, B.; Teixidó, T.; Borges, J.

Usually, in ground-penetrating radar (GPR) datasets, the user defines the limits between the useful signal and the noise through standard filtering to isolate the effective signal as much as possible. However, there are true reflections that mask the coherent reflectors that can be considered noise. In archaeological sites these clutter reflections are caused by scattering with origin in subsurface elements (e....


Exploring the Consistency of Data Collected in Archaeological Geophysics: A Cas...

Pro, C.; Caldeira, B.; Tena, M. T.; Charro, C.; Oliveira, R. J.; Borges, J.; Mayoral, V.

Different geophysical methods applied at the settlement of Villasviejas del Tamuja (Botija, Spain) have identified robust anomalies located at the same position, but some anomalies are reflected by only one method. Furthermore, analysing the spatial correlation of these anomalies is of fundamental importance for obtaining a correct archaeological interpretation. In this work, we analysed the main results of ele...


Shaping Soft Structures Using Bottom-up Layer-by-layer Assembly Technology for ...

Borges, J.; Sousa, C. F. V.; Bjorge, I. M.; Nadine, S.; Correia, C. R.; Patrício, S. G.; Mano, J. F.

Layer-by-layer (LbL) assembly is an easier, inexpensive, and highly versatile bottom-up methodology to modify surfaces and fabricate functional multilayer thin films and nanocomposites with fine-tuned compositions, structures, properties, and functions at the nanoscale. Since the early stages of its development, LbL technology has gathered increasing attention across different fields of application, including i...


Extending the Functionality of Marine-origin Polysaccharides Through Chemical M...

Rodrigues, João M. M.; Castanheira, E. J.; Costa, D. C. S.; Rocha, D. H. A.; Borges, J.; Mano, J. F.

Natural polysaccharides are a major class of biomacromolecules with a high degree of biocompatibility, biodegradability, and ability to mimic the natural extracellular matrix (ECM) microenvironment and, therefore, have been receiving increasing attention. Polysaccharides often exhibit interesting and advantageous properties, including bioactivity, different functional groups, and bioadhesive properties, as well...


Stimuli-responsive Nanocomposite Hydrogels Incorporating Soft Nanoparticles for...

Lavrador, P.; Borges, J.; Gaspar, V. M.; Mano, J. F.

Soft nanoparticles represent a unique class of nanomaterials that can be engineered to react and adapt distinctly in different biological milieus while modulating the presentation of biochemical and biophysical cues to neighbouring receptive cells. This flexibility has fuelled the development of soft nanoparticle-laden nanocomposite hydrogels that are increasingly sophisticated in stimuli-responsiveness and pro...


Near-Surface Characterization of the Lisbon and Lower Tagus Valley Area, Portug...

Carvalho, J.; Dias, R.; Ghose, R.; Teves-Costa, Paula; Borges, J.; Narciso, J.; Pinto, C.; Leote, J.

The Lower Tagus Valley (LTV) region includes the metropolitan area of Lisbon and has the highest population density in Portugal, with about 3.5 million inhab- itants. The LTV has been struck by several historical earthquakes that caused significant economic and human losses, and therefore, earthquake damage mitigation is of great importance. The present research was directed toward preparation of the first deta...


The GO-DACT is an investigator-initiated, national, multicentric randomized pla...

Vieira-Sousa, E; Canhão, H; Alves, P; Rodrigues, AM; Teixeira, F; Tavares-Costa, J; Bernardo, A; Pimenta, S; Pimentel-Santos, .; Gomes, JL; Aguiar, R

The GO-DACT is an investigator-initiated, national, multicentric randomized placebo-controlled double-blinded trial, that assesses dactylitis as primary endpoint. Psoriatic arthritis patients naïve to methotrexate and biologic disease modifying anti-rheumatic drugs, with at least one active dactylitis, were assigned to golimumab in combination with methotrexate or placebo in combination with methotrexate, for 2...


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