4 documents found, page 1 of 1
Dual and sequential drug delivery systems with antimicrobial and bone regenerat...
Rodrigues, Miguel A.; Ferreira, Carla; Borges, João P.; Bernardes, Beatriz G.; Oliveira, Ana L.; Santos, José D.; Lopes, Maria A.Bone defect healing is often compromised by infections acquired during surgery, hindering regeneration. An effective solution should first prevent infection and then promote bone repair. Localised drug-delivery systems capable of dual and sequential release of antimicrobial and bone-regenerative agents represent a promising solution; however, precisely controlling this sequential release remains an unmet challe...
Development of a new chitosan hydrogel for wound dressing
Ribeiro, Maximiano; Espiga, Ana; Silva, Daniela; Baptista, Patrícia; Henriques, Joaquim; Ferreira, Catarina; Silva, Jorge C.; Borges, João P.Wound healing is a complex process involving an integrated response by many different cell types and growth factors in order to achieve rapid restoration of skin architecture and function. The present study evaluated the applicability of a chitosan hydrogel (CH) as a wound dressing. Scanning electron microscopy analysis was used to characterize CH morphology. Fibroblast cells isolated from rat skin were used to...
Electrorheological characterization of dispersions in silicone oil of encapsula...
Brehm, Tiago; Pereira, Gonçalo; Leal, Catarina R.; Gonçalves, Clara; Borges, João P.; Cidade, Maria TeresaThe electrorheological (ER) effect is known as the change in the apparent viscosity upon the application of an external electric field perpendicular to the flow direction. In this work we present the electrorheological behaviour of suspensions in silicone oil of two different dispersed phases: foams of liquid crystal 4-n-penthyl-4'-cyanobiphenyl (5CB) encapsulated in polyvinyl alcohol (PVA) and nano/microsphere...
Helical Twisting of Electrospun Liquid Crystalline Cellulose Micro- and Nanofibers
Canejo, João; Borges, João P.; Godinho, M. Helena; Brogueira, Pedro; Teixeira, Paulo; Terentje, Eugene M.Helically twisted fibers can be produced by electrospinning liquid-crystalline cellulose solutions. Fiber topographies are studied by atomic force microscopy, scanning electron microscopy (see figure) and polarized optical microscopy. The fibers have a nearly universal pitch-to-diameter ratio and comprise both right- and left-handed helices.