74 documents found, page 1 of 8
Burden of Disease and Cost of Illness of Triple-Negative Breast Cancer in Portu...
Silva, Joana; Sousa, Gabriela; Costa, Luís; Brito, Margarida; Oliveira, Sónia; Rodrigues, Bernardo; Ferreira, João; Borges, Margarida; Miguel, LuísBackground: Triple-negative breast cancer accounts for 15% of all breast cancer cases, and it has a lower survival rate and higher incidence of early recurrence, particularly during the first 10 years after diagnosis. Objective: This study aimed to estimate the cost and burden of triple-negative breast cancer among the female population in 2019 in Portugal from a societal perspective. Methods: The prevalence of...
Custos e Consequências da Doença Renal Crónica em Pessoas com Diabetes em Portu...
Borges, Margarida; Almeida, Edgar; Alves, Rui; Ascenção, Raquel; Bigotte Vieira, Miguel; Bulhosa, Carolina; Costa, João; S Duarte, Gonçalo; Falcão, LuísIntroduction: Chronic kidney disease is the fastest-growing chronic disease in terms of prevalence and one of the biggest causes of global mortality according to the Global Burden of Disease Collaboration. This study aimed to project the natural disease progression of this disease in people with diabetes, and to quantify the costs and consequences in the Portuguese context. This was achieved by developing an an...
Custos e consequências da doença renal crónica em pessoas com diabetes em Portu...
Borges, Margarida; Almeida, Edgar; Alves, Rui; Ascenção, Raquel; Vieira, Miguel Bigotte; Bulhosa, Carolina; Costa, João; Duarte, Gonçalo S.Introdução: A doença renal crónica é a doença crónica com maior crescimento de prevalência, e uma das maiores causas de mortalidade global de acordo com o Global Burden of Disease Collaboration. O presente estudo teve como objetivo projetar a evolução desta doença em pessoas com diabetes, de modo a quantificar os custos e consequências no contexto português. Tal foi conseguido através do desenvolvimento e param...
The impact on productivity costs of reducing unemployment in patients with adva...
Matos, Leonor Vasconcelos de; Borges, Margarida; Oliveira, Ana Teresa; Bulhosa, Carolina; Miguel, Luís Silva; Freitas, Tiago Fidalgo de; Cunha, RenatoThis study aimed to characterize the employment status and work-related conditions of patients with advanced breast cancer (ABC) in Portugal and quantify the productivity costs of premature abandonment of the work market while evaluating strategies to promote employment. The analysis was based on a cumulative incidence model for estimation of ABC prevalence and on a cross-sectional study characterizing the empl...
Burden of Disease and Cost of Illness of Overweight and Obesity in Portugal
Borges, Margarida; Sampaio, Filipa; Costa, João; Freitas, Paula; Matias Dias, Carlos; Gaio, Vânia; Conde, Vasco; Figueira, Débora; Pinheiro, BernardeteIntroduction: The prevalence of overweight and obesity has increased in the last decades, posing significant health and economic impacts globally. These conditions are related to several non-communicable diseases, including cardiovascular disease, type II diabetes, and cancer. This study estimated the disease burden and healthcare costs associated with overweight and obesity in the adult population in mainland ...
Cost-effectiveness of Semaglutide 2.4 mg in chronic weight management in Portugal
Silva Miguel, Luís; Soares, Mariana; Olivieri, Anamaria; Sampaio, Filipa; Lamotte, Mark; Shukla, Suramya; Conde, Vasco; Freitas, Paula; Costa, JoãoBackground: Obesity and overweight are a significant public health concern. Subcutaneous semaglutide 2.4 mg injection is a glucagon-like peptide-1 (GLP-1) analogue approved by the European Medicines Agency as an adjunct to a reduced calorie diet and increased physical activity (diet and exercise, D&E) for the treatment obesity and overweight in the presence of at least one weight related comorbidity. This study...
In-hospital mortality of high-risk pulmonary embolism: a nationwide population-...
Calé, R.; Ascenção, Raquel; Bulhosa, C.; Pereira, Helder; Borges, Margarida; Costa, J.; Caldeira, DanielBackground: The mortality associated with high-risk pulmonary embolism (PE) is remarkably high, and reperfusion to unload right ventricle should be a priority. However, several registries report reperfusion underuse. In Portugal, epidemiological data about the incidence, rate of reperfusion and mortality of high-risk PE are not known. Methods: Nationwide population-based temporal trend study in the incidence an...
The Cost of Meningococcal Meningitis in Portugal
Rodrigues, Fernanda; Pinheiro, Bernardete; Guerreiro, Rita; Gouveia, Miguel; Eloi, João; Alves, Cristina; Castela, Guilherme; Oliveira, AlexandraIntroduction: Invasive meningococcal disease (IMD) is an infection caused by the bacterium Neisseria meningitidis, and a major cause of meningitis (MM) and/or septicemia (MS). The aim of this study is to estimate the costs of IMD (MM and MS) for Portuguese state.Methods: To estimate the costs associated with IMD, a model was developed, where patients can have one of three outcomes: survive without sequelae, sur...
Oral Anticoagulation and the Incidence of Stroke Associated with Atrial Fibrill...
Ascenção, Raquel; Gil, Madalena; Lourenço, Francisco; Caldeira, Daniel; Oliveira, Rosário; Borges, Margarida; Silva Miguel, Luís; Costa, JoãoIntroduction: Atrial fibrillation is the most prevalent persistent dysrhythmia, contributing to a significant social and economic burden. The main objective of this study was to evaluate the association between oral anticoagulant use and the incidence of stroke associated with atrial fibrillation, in mainland Portugal.Methods: The number of episodes of inpatient care with a main diagnosis of stroke and an addit...
Atherosclerosis in the primary health care setting: a real-word data study
Ascenção, Raquel; Alarcão, Joana; Araújo, Francisco; Costa, João; Fiorentino, Francesca; Gil, Victor; Gouveia, Miguel; Lourenço, FranciscoIntroduction and Objectives: To characterize patients with atherosclerosis, a disease with a high socioeconomic impact, in the Lisbon and Tagus Valley Health Region. Methods: A cross-sectional observational study was carried out through the Lisbon and Tagus Valley Regional Health Administration primary health care database, extracting data on the clinical and demographic characteristics and resource use of adul...