[Excerpt] Introduction Orthopedic implants have been widely used to restore the function of load-bearing joints, reducing pain and improving the life quality of millions of people every year. These devices are, however, prone to microbial infection, which remains a major cause of morbidity and mortality in modern Healthcare. The development of novel approaches to confer the surfaces of orthopedic implants with ...
Financiadora de Estudos e Projetos; In this dissertation we propose new models for survival with cure fraction to describe the biological mechanism of the event of interest (cancer) in studies of carcinogenesis in the presence of competing causes latent independent or correlated. The formulation of new models is based on stochastic modeling of the occurrence of tumors through three stages: initiation of a tumor...