2 documents found, page 1 of 1
Subjective sleep parameters in prodromal Alzheimer’s disease: a case-control study
Borges,Conrado R.; Piovezan,Ronaldo D.; Poyares,Dalva R.; Busatto Filho,Geraldo; Studart-Neto,Adalberto; Coutinho,Artur M.; Tufik,SergioObjective: People with Alzheimer’s disease (AD) dementia have impaired sleep. However, the characteristics of sleep in the early stages of AD are not well known, and studies with the aid of biomarkers are lacking. We assessed the subjective sleep characteristics of non-demented older adults and compared their amyloid profiles. Methods: We enrolled 30 participants aged ≥ 60 years, with no dementia or major clini...
Dopamine transporter imaging in clinically unclear cases of parkinsonism and th...
Utiumi,Marco A. T.; Felício,André C.; Borges,Conrado R.; Braatz,Vera L.; Rezende,Sheyla A. S.; Munhoz,Renato P.; Bressan,Rodrigo A.; Ferraz,Henrique B.The clinical diagnosis of Parkinson's disease (PD) is susceptible to misdiagnosis, especially in the earlier stages of the disease. Recently, in vivo imaging techniques assessing the presynaptic dopamine transporter (DAT) have emerged as a useful tool in PD diagnosis, improving its accuracy. OBJECTIVE: It was to illustrate the clinical usefulness of a brain single-photon emission computed tomography (SPECT) DAT...