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Zoon Balanitis and Lichen Sclerosus: An Uncommon Association
Garrido, Pedro Miguel; Aguado-Lobo, Marta; Soares de Almeida, Luís; Borges da Costa, JoãoZoon balanitis and lichen sclerosus are both chronic inflammatory disorders of the genital mucosa that usually affect middle-aged or elderly uncircumcised men.Although the precise etiology of Zoon balanitis is still unclear, a pathogenic role of irritant and mechanical factors has been suggested. Therefore, foreskin sclerosis and phimosis caused by male genital lichen sclerosus may trigger the development of Zo...
Chlamydia Trachomatis Genital Infections among Portuguese Adolescents
Vaz Pereira, Francisco; Borges da Costa, JoãoAdolescents (between 10 and 19 years old) are an age group with a high prevalence of sexually transmitted infections (STI), due to biological and socio-behavioural factors. In Portugal, adolescents show poor condom adherence, have multiple sexual partners, poor sex education and high reinfection rates. In this age group, genital infection by Chlamydia trachomatis is the most prevalent STI, whose asymptomatic co...
Gonorrhea: Antimicrobial Resistance and New Drugs
Queirós, Catarina Soares; Borges da Costa, JoãoThe global burden of sexually transmitted infections remains high, with significant associated morbidity and mortality. Gonorrhea is the second most notified sexually transmitted infection in Europe, and its incidence has been increasing in the last years. Although traditionally considered a treatable infection, antimicrobial resistance of Neisseria gonorrhoeaeincludes at present also macrolides, tetracyclines,...
Patologia anogenital por papilomavírus humano em doentes com vírus da imunodefi...
Teixeira, Álvaro Rodrigues; Borges da Costa, JoãoA terapêutica HAART diminuiu a incidência de doenças oportunísticas, mas não teve efeito na diminuição das infecções provocadas por HPV. As alterações anogenitais mais comuns são os condilomas acuminados benignos, mas podem ocorrer lesões pré-malignas e malignas como a neoplasia intraepitelial anal e o cancro anal. A incidência e prevalência das alterações dermatológicas por HPV têm vindo a aumentar nos doentes...
Crusted Scabies in an HIV-Infected Patient
Trigo, Diva; Pina, Ana; Lopes, Maria João; Pacheco, Patrícia; Soares de Almeida, Luís; Borges da Costa, JoãoHIV predisposes infected patients to multiple skin diseases that frequently exhibit atypical clinical presentations. The authors report the case of a 57-year-old man with severe HIV-related immunosuppression who developed a generalized pruritic dermatosis during prolonged hospitalization. Taking into account the patient’s status, his complaints and distribution of lesions, diagnosis of scabies was considered, a...
HIV Infection: Epidemiology, Natural History and Diagnosis
Trigo, Diva; Borges da Costa, JoãoIn the last 35 years, major progresses have been accomplished in the prevention, diagnosis and treatment of HIV infection, with reduction of the incidence of infection in Portugal, in the last decade. Nevertheless, there is still a high rate of late diagnosis, with individual and populational adverse outcomes. This paper aims to: present the current situation of HIV infection in Portugal, briefly review the nat...
CHEMOPROPHYLAXIS OF GENITAL HERPES
Teixeira, Ana Isabel; Vaz, Nuno; Borges da Costa, JoãoGenital herpes is among the most common sexually transmitted diseases worldwide. Recurrent genital herpes is associated with major morbidity. Therefore, suppressive therapy plays an important role in the life quality of these patients. There are no established guidelines regarding the criteria for initiation of prophylactic therapy, although there is evidence for it after 6 recurrences per year. Drugs approved ...
GENITAL CHLAMYDIA TRACHOMATIS INFECTION IN A SEXUALLY TRANSMITTED INFECTION CLI...
Travassos, Ana Rita; Borges da Costa, João; Azevedo, Jacinta; Santo, IreneIntroduction: Chlamydia trachomatis genital infection (Ct) is now the most common sexually transmitted bacterial infection (STI) diagnosed in United Kingdom and in United States and its prevalence is highest in persons younger than 25 years. Asymptomatic infection is also common among both men and women.Objectives: To assess epidemiological characteristics and prevalence of Ct in a population of patients attend...
REACTIVE ARTHRITIS (SYN: REITER’S SYNDROME)
Antunes, João; Borges da Costa, João; Sacramento Marques, ManuelReactive arthritis, previously known as Reiter’s Syndrome, is the classic triad of arthritis, urethritis and conjunctivitis, which occurs after an acute episode of genito-urinary or gastrointestinal infection. In adults, the most frequent cause is infection by Chlamydia trahomatis. It may also present as an incomplete triad or be associated with dermatological or visceral symptoms. It is classified as a seroneg...