2 documents found, page 1 of 1
Effective immunotherapy against canine visceral leishmaniasis with the FML-vacc...
Borja Cabrera, Gulnara Patricia; Mendes, Amanda Cruz; Souza, Edilma Paraguai de; Okada, Lilian Y. Hashimoto; Trivellato, Fernando Antonio de AssisThe potential effect of the fucose mannose ligand (FML)-vaccine on immunotherapy of canine visceral leishmaniasis was assayed on five mongrel dogs experimentally infected withLeishmania donovani and on 21 Leishmania chagasi naturally infected dogs when seropositive to FML but completely asymptomatic. The clinical signs of the experimentally infected, symptomatic dogs only disappeared after the complete vaccinat...
Immunotherapy against experimental canine visceral leishmaniasis with the sapon...
Santos, Fernanda Nunes; Borja Cabrera, Gulnara Patricia; Myashiro, L. M.; Grechi, Juliana; Reis, Alexandre Barbosa; Moreira, Márcio Antônio BatistelaIn order to assess the immunotherapeutic potential on canine visceral leishmaniasis of the Leishmune ® vaccine, formulated with an increased adjuvant concentration (1 mg of saponin rather than 0.5 mg), 24 mongrel dogs were infected with Leishmania (L.) chagasi . The enriched-Leishmune ® vaccine was injected on month 6, 7 and 8 after infection, when animals were seropositive and symptomatic. The control group we...