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ACE2 diversity in placental mammals reveals the evolutionary strategy of SARS-C...

Sampaio de Oliveira Fam, Bibiana; Vargas-Pinilla, Pedro; Guerra Amorim, Carlos Eduardo; Sortica, Vinicius; Bortolini, Maria Cátira

The recent emergence of SARS-CoV-2 is responsible for the current pandemic of COVID-19, which uses the human membrane protein ACE2 as a gateway to the host-cell infection. We perform comparative genomic analysis of 70 ACE2 placental mammal orthologues to identify variations and contribute to the understanding of evolutionary dynamics behind this successful adaptation to infect humans. Our results reveal that 4%...

Date: 2020   |   Origin: Oasisbr





African-derived South American Populations: A History of Symmetrical and Asymme...

Bortolini, Maria Cátira; Silva Junior, Wilson Araújo da; Guerra, Dinorah Castro de; Remonatto, Gabriela; Mirandola, Rosana; Hutz, Mara H.

Texto completo. Acesso restrito. p.551–563; Submitted by Santiago Fabio (fabio.ssantiago@hotmail.com) on 2013-07-31T18:49:49Z No. of bitstreams: 2 2222222222222.pdf: 108504 bytes, checksum: 8cb5a73412cf3c4eccadce21486ab759 (MD5) 2222222222222.pdf: 108504 bytes, checksum: 8cb5a73412cf3c4eccadce21486ab759 (MD5); Approved for entry into archive by Rodrigo Meirelles (rodrigomei@ufba.br) on 2013-11-03T15:03:25Z (GMT...

Date: 2013   |   Origin: Oasisbr


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