Hypereosinophilic syndromes are rare in children. Sporadic, mild-severity FIP1L1-platelet-derived growth factor receptor α (PDGFRα) rearrangement cases have been reported, mainly in boys. We present the case of a 5-year-old girl referred from her African country of birth, due to severe constitutional symptoms, multifocal bone pain, headache, gastrointestinal complaints, cardiomyopathy and unexplained hypereosin...
Introduction and Aims: Nephrolithiasis incidence in children has increased considerably. It is associated with substantial morbidity, recurrence and increased adulthood cardiovascular risk and chronic kidney disease. A thorough investigation is essential, as rare forms of urolithiasis have increased risk of renal failure. We aim to determine the epidemiology and outcomes of a pediatric population with nephrolit...
Introdução: As infecções respiratórias baixas são a principal causa de mortalidade em crianças até aos 5 anos. A utilização do painel rápido multiplex por PCR melhora a identificação do diagnóstico etiológico. Objetivos: Comparar a evolução de infecções respiratórias víricas com um ou mais agente isolado em crianças admitidas por insuficiência respiratória aguda (IRA) em cuidados intensivos. Métodos: Estudo ret...
An increased risk of severe and fatal Israeli spotted fever (ISF) has been observed in adults, mostly associated with ISF strain. Here, we report a case of severe ISF with multiorgan failure in a Portuguese child.