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Hypereosinophilia and Severe Bone Disease in an African Child: An Unexpected Di...

Bota, S; Alves, P; Constantino, C; Maia, R

Hypereosinophilic syndromes are rare in children. Sporadic, mild-severity FIP1L1-platelet-derived growth factor receptor α (PDGFRα) rearrangement cases have been reported, mainly in boys. We present the case of a 5-year-old girl referred from her African country of birth, due to severe constitutional symptoms, multifocal bone pain, headache, gastrointestinal complaints, cardiomyopathy and unexplained hypereosin...


Nephrolithiasis in a Portuguese Pediatric Population

Andrade, J; Bota, S; Francisco, T; Santos, R; Neto, G; Abranches, M

Introduction and Aims: Nephrolithiasis incidence in children has increased considerably. It is associated with substantial morbidity, recurrence and increased adulthood cardiovascular risk and chronic kidney disease. A thorough investigation is essential, as rare forms of urolithiasis have increased risk of renal failure. We aim to determine the epidemiology and outcomes of a pediatric population with nephrolit...


Impacto das Infeções Respiratórias Viricas Múltiplas na Evolução de Crianças Gr...

Verdelho Andrade, J; Bota, S; Marques, F; Casimiro, A; Estrada, J; Santos, M

Introdução: As infecções respiratórias baixas são a principal causa de mortalidade em crianças até aos 5 anos. A utilização do painel rápido multiplex por PCR melhora a identificação do diagnóstico etiológico. Objetivos: Comparar a evolução de infecções respiratórias víricas com um ou mais agente isolado em crianças admitidas por insuficiência respiratória aguda (IRA) em cuidados intensivos. Métodos: Estudo ret...


Severe Israeli Spotted Fever with Multiorgan Failure in a Child

Bota, S; Sousa, R; Santos, M; Varandas, L; Gouveia, C

An increased risk of severe and fatal Israeli spotted fever (ISF) has been observed in adults, mostly associated with ISF strain. Here, we report a case of severe ISF with multiorgan failure in a Portuguese child.


CAT-SCRATCH Disease: Still a Challenge

Bota, S; Jacinto, S; Ferreira, C; Santos, AS; Varandas, L; Gouveia, C



A Case of Complicated Ascaris Infection

Moreira, T; Bota, S; Carvalho, MR; Cordeiro, AI; Gouveia, C; Varandas, L


Clostridium Difficile in a Tertiary Pediatric Hospital

Bota, S; Varandas, L; Cordeiro-Ferreira, G; Gouveia, C



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