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Novel concept of exosome-like liposomes for the treatment of Alzheimer's disease
Fernandes, Mário; Lopes, I.; Magalhães, Luana; Sárria, Marisa P.; Machado, Raul; Sousa, João Carlos; Botelho, Cláudia Manuela da Cunha FerreiraExosomes are cell-derived vesicles that act as carriers for proteins and nucleic acids, with therapeutic potential and high biocompatibility. We propose a new concept of exosome-like liposomes for controlled delivery. The goal of this work was to develop a new type of liposomes with a unique mixture of phospholipids, similar to naturally occurring exosomes but overcoming their limitations of heterogeneity and l...
Data: 2021
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Origem: RepositóriUM - Universidade do Minho
Silicon-substituted hydroxyapatite for biomedical applications
Botelho, Cláudia Manuela da Cunha Ferreira
Data: 2005
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Origem: Repositório Aberto da Universidade do Porto