10 documents found, page 1 of 1
ABORDAGEM MÉDICO-CIRÚRGICA NO TRATAMENTO MULTIMODAL DE CARCINOMA DE CÉLULAS ESC...
Guimarães, Tarcísio; Cardoso, Karla; Moraes, Joana; Moraes, Carlos; Botelho, Filomena; Alexandre, NunoO carcinoma de células escamosas representa a neoplasia cutânea maligna mais frequente nos gatos domésticos4 e sendo mais prevalente do que na maioria das outras espécies2. Acomete com maior frequência plano nasal, pálpebras, orelha e lábios. A sua ocorrência está associada a regiões de alopecia, pouca pigmentação, exposição aos raios solares, vírus, lesões inflamatórias crônicas, entre outros fatores4. Variado...
DIMETHYLPOLYSILOXANE AS AN OPTION FOR CLINICAL TREATMENT OF CORNEAL EDEMA IN A ...
Guimarães, Tarcísio; Cardoso, Karla; Botelho, Filomena; Laranjo, Mafalda; Alexandre, NunoIntroduction Corneal edema manifests as a diffuse blue-gray opacity. These corneal lesion is due to increased water bonds between stromal collagen fibers4 and may occur secondary to epithelial ulcerations, blood vessel growth and corneal endothelial disorders4. The inciting mechanism is due to the loss or functional defect of the corneal endothelium and results in a very diffuse edema4. When endothelial disorde...
LIPOSSARCOMA IN GUINEA PIG: A CASE REPORT
Guimarães, Tarcísio; Cardoso, Karla; Moraes, Joana; Moraes, Carlos; Botelho, Filomena; Laranjo, Mafalda; Alexandre, NunoIntroduction Liposarcomas are malignant tumors of adipocytic differentiation1 , of rare incidence, affecting animals and humans2 . According to the clinical and pathological characteristics of liposarcoma, it can be classified into well-differentiated, undifferentiated, myxoid and pleomorphic3 . Surgical excision is recommended, but recurrence4 and metastasis may occur1 . Objectives The objective of this study ...
SURGICAL RESOLUTION AFTER MULTIMODAL TREATMENT IN A DOG WITH GRANULOMATOUS NODU...
Guimarães, Tarcísio; Cardoso, Karla; Botelho, Filomena; Laranjo, Mafalda; Rozin, A.; Tralhão, Pedro; Alexandre, NunoIntroduction Granulomatous nodular episcleritis(GNE) is a mixed lymphocytic and granulomatous nodular inflammation of the conjunctiva or adjacent sclera4, rarely described in dogs. Defined as an idiopathic conjunctiva and scleral primary disease, is presumed to be an immune-mediated disorder; although may also be derived from secondary disease1.Clinically characterized by an elevated, non-painful, single or mul...
RECONSTRUÇÃO PALPEBRAL BEM-SUCEDIDA E REPARO INFRAORBITAL USANDO UMA TÉCNICA DE...
Guimarães, Tarcísio; Cardoso, Karla; Botelho, Filomena; Alexandre, Nuno; Pacheco, Magda; Olivério, Pedro; Faim, Susana; Figueira, Ana CatarinaIntrodução A complexidade das alterações palpebrais exige do cirurgião amplo conhecimento anatómico e domínio de várias técnicas cirúrgicas para o tratamento bem-sucedido1,2. A técnica de Mustardé é usada na medicina humana para reconstruir defeitos que envolvem muita ou toda a pálpebra inferior e região infraorbital3. Tecnicamente, consiste num grande retalho de avanço da rotação da pele da bochecha, realizado...
Plasmatic Oxidative and Metabonomic Profile of Patients with Different Degrees ...
Silva-Vaz, Pedro; Jarak, Ivana; Rato, Luis; Oliveira, Pedro F.; Morgado-Nunes, Sara; Paulino, Aida; Castelo-Branco, Miguel; Botelho, FilomenaAcute pancreatitis (AP) is an inflammatory process of the pancreas with variable involvement of the pancreatic and peripancreatic tissues and remote organ systems. The main goal of this study was to evaluate the inflammatory biomarkers, oxidative stress (OS), and plasma metabolome of patients with different degrees of biliary AP severity to improve its prognosis. Twenty-nine patients with biliary AP and 11 heal...
Dental caries and bacterial load in saliva and dental biofilm of type 1 diabeti...
Coelho, Ana; Paula, Anabela; Mota, Marta; Laranjo, Mafalda; Abrantes, Margarida; Carrilho, Francisco; Ferreira, Manuel; Silva, Mário; Botelho, FilomenaObjectives: Since most of the studies evaluates diabetics on multiple daily injections therapy and continuous subcutaneous insulin infusion may help gain better metabolic control and prevent complications, the objective of this study was to evaluate the prevalence of dental caries, the unstimulated salivary flow rate and the total bacteria load, Streptococcus spp. levels and Lactobacillus spp. levels in saliva ...
Doping β-TCP as a Strategy for Enhancing the Regenerative Potential of Composit...
Ferreira, Manuel M.; Brito, Ana F.; Brazete, Daniela; Pereira, Inês C.; Carrilho, Eunice; Abrantes, Ana M.; Pires, Ana S.; Aguiar, Maria JThe present work aims at evaluating the potential gains derived from partially replacing calcium in resorbable β-tricalcium phosphate (β-TCP) by two different molar percentages of strontium (5, 10) and zinc (1, 2), concomitantly with a fixed molar percentage (0.5) of manganese. Synthetic granular composite bone filling grafts consisting of doped β-TCP and an alkali-free bioactive glass were prepared and implant...
2-Bromo-5-hydroxyphenylporphyrins for photodynamic therapy: photosensitization ...
Laranjo, Mafalda; Serra, Arménio C.; Abrantes, Margarida; Piñeiro, Marta; Gonçalves, Ana C.; Casalta-Lopes, João; Carvalho, LinaPhotodynamic therapy (PDT) is a therapeutic modality capable of inducing cell death by oxidative stress through activation of a sensitizer by light. Aryl-porphyrin with hydroxyl groups are good photosensitizers and presence of bromine atoms can enhance the photodynamic activity through heavy atom effect. These facts and our previous work made pertinent to compare the photodynamic capacity of tetraaryl brominate...
Effect of ionizing radiation on rat peritoneal macrophages
Cunha, Ana; Lourenço, António; Cancela, João; Castelhano, João; Carvalho, Sara; Saiote, Ana; Matias, Áurea; Reis, Emília; Lopes, Carmo; Santos, AnaThis study aims to evaluate the survival rate of peritoneal rat macrophages after exposure to 3 & 6 Gy ionizing radiation fields, respectively. Cells were cultured in multiwell plates (37 ºC, 5% CO2), separated in 3 groups: GI–control; GII-cells irradiated with 3 Gy; GIII–cells irradiated with 6 Gy, using a 4 MeV particle accelerator. After irradiation cells were incubated for 2h30 = T0, 13 h = T1, 20 h = T...