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Influence of Aldehyde Dehydrogenase Inhibition on Stemness of Endometrial Cance...

Serambeque, Beatriz; Mestre, Catarina; Barros, Gabriela; Marques Teixo, Ricardo Jorge; Marto, Carlos Miguel; Gonçalves, Ana Cristina

Publisher Copyright: © 2024 by the authors.; Endometrial cancer is one of the most common gynaecological malignancies. Although often diagnosed at an early stage, there is a subset of patients with recurrent and metastatic disease for whom current treatments are not effective. Cancer stem cells (CSCs) play a pivotal role in triggering tumorigenesis, disease progression, recurrence, and metastasis, as high aldeh...


Kinetics of radium-223 and its effects on survival, proliferation and DNA damag...

Marques, IA; Abrantes, AM; Pires, AS; Neves, AR; Caramelo, FJ; Rodrigues, T; Matafome, P; Tavares-da-Silva, E; Gonçalves, AC; Pereira, CC; Teixeira, JP

Background Metastatic castration-resistant prostate cancer (mCRPC) is associated with a very unfavorable prognosis. At this advanced stage of the disease, there are several therapeutic strategies approved in recent times, being one of them Radium-223 dichloride (Radium-223). However, its mechanisms of action and the process that conducts to cell death are not fully understood. Given this, our main goal is to ch...


Evaluation of the efficacy of dentin hypersensitivity treatments - a systematic...

Marto, CM; Baptista Paula, A; Nunes, T; Pimenta, M; Abrantes, AM; Pires, AS; Laranjo, M; Coelho, A; Donato, H; Botelho, MF; Marques Ferreira, M

OBJECTIVES: To compare the treatments used to treat dentin hypersensitivity (DH), based on its efficacy and effect duration. METHODS: Medline/PubMed, Cochrane Library, EMBASE, and ClinicalTrials were searched for articles published between January 1st , 2008 and November 14th , 2018, in English, Portuguese or Spanish, reporting clinical trials, completed and with results. This systematic review protocol was reg...


Array-comparative genomic hybridization as a novel high-throughput approach in ...

Neves, AR; Abrantes, AM; Ribeiro, IP; Marques, IA; Marques, V; Tavares da Silva, E; Carreira, IM; Figueiredo, A; Botelho, MF


SIRT1 and mTOR interplay in bladder cancer: a potential therapeutic target

Oliveira, P; Silva, AM; Tavares da Silva, E; Jarak, I; Abrantes, M; Botelho, MF; Figueiredo, A; Silva, BM; Pereira, JA; Oliveira, PF; Alves, MG


The future of selective oncology therapy applied to urological tumors - plasma ...

Tavares da Silva, E; Almeida-Ferreira, C; Silva-Teixeira, R; Eliseu, M; Laranjo, M; Marques, I; Neves, R; Abrantes, AM; Caramelo, F; Figueiredo, A


Evaluation of the impact of diabetes mellitus on the biology of prostate cancer

Antunes, H; Teixo, R; Carvalho, J; Eliseu, M; Marques, I; Mamede, A; Neves, R; Oliveira, R; Tavares da Silva, E; Abrantes, M; Parada, B; Botelho, MF


The effect of cold atmospheric plasma in bladder cancer cell

Tavares da Silva, E; Neves, AR; Abrantes, AM; Silva-Teixeira, R; Figueiredo, A; Botelho, MF


Selective ablating urologic cancers with cold atmospheric plasma

Almeida-Ferreira, C; Tavares da Silva, E; Silva-Teixeira, R; Laranjo, M; Marques, I; Neves, R; Abrantes, AM; Caramelo, F; Figueiredo, A; Botelho, MF


Oxidative Stress, DNA, Cell Cycle/Cell Cycle Associated Proteins and Multidrug ...

Mamede, AC; Guerra, S; Laranjo, M; Santos, K; Carvalho, MJ; Carvalheiro, T; Moura, P; Paiva, A; Abrantes, AM; Maia, CJ; Botelho, MF

The anticancer effects of human amniotic membrane (hAM) have been studied over the last decade. However, the action mechanisms responsible for these effects are not fully understood until now. Previously results reported by our team proved that hAM is able to induce cytotoxicity and cell death in hepatocellular carcinoma (HCC), a worldwide high incident and mortal cancer. Therefore, this experimental study aime...


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