3 documents found, page 1 of 1
A computational method for the identification of dengue, zika and chikungunya v...
Fonseca, Vagner S.; Libin, Pieter J. K.; Theys, Kristof; Faria, Nuno Rodrigues; Nunes, Márcio Roberto Texeira; Restovic, Maria I.; Freire, MuriloIn recent years, an increasing number of outbreaks of Dengue, Chikungunya and Zika viruses have been reported in Asia and the Americas. Monitoring virus genotype diversity is crucial to understand the emergence and spread of outbreaks, both aspects that are vital to develop effective prevention and treatment strategies. Hence, we developed an efficient method to classify virus sequences with respect to their sp...
A public HTLV-1 molecular epidemiology database for sequence management and dat...
Araujo , Thessika Hialla Almeida; Souza-Brito, Leandro Inacio; Libin,, Pieter; Deforche, Koen; Edwards, Dustin; Albuquerque-Junior, Antonio Eduardo deIt is estimated that 15 to 20 million people are infected with the human T-cell lymphotropic virus type 1 (HTLV-1). At present, there are more than 2,000 unique HTLV-1 isolate sequences published. A central database to aggregate sequence information from a range of epidemiological aspects including HTLV-1 infections, pathogenesis, origins, and evolutionary dynamics would be useful to scientists and physicians w...
HIV-1 gp120 N-linked glycosylation differs between plasma and leukocyte compart...
Ho, Yung Shwen; Abecasis, Ana B; Theys, Kristof; Deforche, Koen; Dwyer, Dominic E; Charleston, Michael; Vandamme, Anne Mieke; Saksena, Nitin KBACKGROUND: N-linked glycosylation is a major mechanism for minimizing virus neutralizing antibody response and is present on the Human Immunodeficiency Virus (HIV) envelope glycoprotein. Although it is known that glycosylation changes can dramatically influence virus recognition by the host antibody, the actual contribution of compartmental differences in N-linked glycosylation patterns remains unclear. METHOD...