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Nanotechnology in ligature-induced periodontitis: protective effect of a doxycy...

Botelho,Marco Antonio; Martins,Jose Galberto; Ruela,Ronaldo Sousa; Queiroz,Dinalva Brito; Ruela,Wagner Sousa

OBJECTIVES: The aim of this study was to test the efficacy of a locally applied 8.5% nanostructured doxycycline (DOX) gel in preventing alveolar bone loss in experimental periodontal disease (EPD) in rats by using the tapping mode atomic force microscopy (AFM). MATERIAL AND METHODS: EPD was induced in 24 Wistar rats. Animals were treated with the doxycycline gel topically, immediately after EPD induction, and 3...

Date: 2010   |   Origin: Oasisbr

Effect of a novel essential oil mouthrinse without alcohol on gingivitis: a dou...

Botelho,Marco Antonio; Bezerra Filho,José Gomes; Correa,Luciano Lima; Fonseca,Said Gonçalves da Cruz; Montenegro,Danusa; Gapski,Ricardo

Several different plant extracts have been evaluated with respect to their antimicrobial effects against oral pathogens and for reduction of gingivitis. Given that a large number of these substances have been associated with significant side effects that contraindicate their long-term use, new compounds need to be tested. The aim of this study was to assess the short-term safety and efficacy of a Lippia sidoide...

Date: 2007   |   Origin: Oasisbr

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